The cell-surface molecules encoded by the genes of Human Leukocyte Antigen (HLA) present peptides to T-cells, which upon recognizing them as foreign, initiate a specific immune response. HLA genes have been associated with a variety of infectious and autoimmune diseases. However, the exact mechanisms that underlie this association, and by that, modulate the antagonistic selection on HLA genes remain elusive. In order to elucidate them in my thesis, I started by investigating the basis of HLA heterozygote advantage against HIV-1 progression using a dataset of 6,311 HIV-1 infected individuals. The individual-specific HLA-bound HIV-1 peptide repertoires suggested that HLA heterozygote advantage could be mediated by a broader array of HLA- bou...
This study aims to contribute to the college retention literature by examining two psychosocial cons...
The old-age population is increasing at a considerably faster rate than the worlds total population....
Systematic error variance (SEV) is one of sources that make a measurement noninvariant (DeShon, 2004...
The cell-surface molecules encoded by the genes of Human Leukocyte Antigen (HLA) present peptides to...
The interaction between hosts and pathogens represents a major driver of their evolution, and a core...
The Ten-eleven translocation (TET) enzymes oxidize the DNA base 5-methylcytosine (5mC) to 5-hydroxym...
PurposeThere has been little qualitative research on abortion care in the UK, which explores the voi...
Coronary Artery Disease (CAD) is responsible for 1 death every minute in the US. Angioplasty with th...
This report is a focused review and discussion of the life safety and fire protection design of Cal ...
Multiple Sclerosis (MS) is an immune mediated disease of the central nervous system (CNS). The aetio...
In 1959, physicist and Nobel laureate-to-be Richard Feynman held his famous speech “There’s Plenty o...
This guidebook describes in detail the procedures and format which your thesis must fulfil before t...
Over the past decades many western countries have witnessed an epidemic rise in obesity, insulin res...
The goal of this thesis is to study new ways to interact with the nervous system in case of damage o...
Rationale +/- 3,4-Methylenedioxymethamphetamine (MDMA) produces effects on a number of neurochemical...
This study aims to contribute to the college retention literature by examining two psychosocial cons...
The old-age population is increasing at a considerably faster rate than the worlds total population....
Systematic error variance (SEV) is one of sources that make a measurement noninvariant (DeShon, 2004...
The cell-surface molecules encoded by the genes of Human Leukocyte Antigen (HLA) present peptides to...
The interaction between hosts and pathogens represents a major driver of their evolution, and a core...
The Ten-eleven translocation (TET) enzymes oxidize the DNA base 5-methylcytosine (5mC) to 5-hydroxym...
PurposeThere has been little qualitative research on abortion care in the UK, which explores the voi...
Coronary Artery Disease (CAD) is responsible for 1 death every minute in the US. Angioplasty with th...
This report is a focused review and discussion of the life safety and fire protection design of Cal ...
Multiple Sclerosis (MS) is an immune mediated disease of the central nervous system (CNS). The aetio...
In 1959, physicist and Nobel laureate-to-be Richard Feynman held his famous speech “There’s Plenty o...
This guidebook describes in detail the procedures and format which your thesis must fulfil before t...
Over the past decades many western countries have witnessed an epidemic rise in obesity, insulin res...
The goal of this thesis is to study new ways to interact with the nervous system in case of damage o...
Rationale +/- 3,4-Methylenedioxymethamphetamine (MDMA) produces effects on a number of neurochemical...
This study aims to contribute to the college retention literature by examining two psychosocial cons...
The old-age population is increasing at a considerably faster rate than the worlds total population....
Systematic error variance (SEV) is one of sources that make a measurement noninvariant (DeShon, 2004...