Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference

WOS: 000408995000002PubMed ID: 28319600As pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mechanisms of tolerance and the role of donor-specific antibodies, considering ways to expand donor pool, minimizing long-term side effects of immunosuppression, and fine-tuning surgical techniques to minimize biliary and vascular complications.ESPGHAN; UEG; Orphan Europe; AstellasAstellas Pharmaceuticals; NovartisNovartis; Billy Rubin eV; Integrated Research and Treatment Center Transplantation; German Federal Ministry of Education and ResearchFederal Ministry of Education & Research (BMBF); MHH Plus Foundation; Swiss Science FoundationSwiss National Science Foundation (SNSF) [PP00P3_139021]The authors of this manuscript have conflicts of interest to disclose as described by the Liver Transplantation. The monothematic conference entitled "Current paradigms and novel strategies in pediatric liver transplantation'' was sponsored in part by the following: ESPGHAN, UEG, Orphan Europe, Astellas, Novartis, Billy Rubin eV, Integrated Research and Treatment Center Transplantation, the German Federal Ministry of Education and Research, and the MHH Plus Foundation. C.T. is supported by a professorship by the Swiss Science Foundation (PP00P3_139021)