Reproductive and sexual functions in schizophrenia: Effects of antipsychotic treatment [Şizofrenide üreme ve cinsel işlevler: Antipsikotik sagaltimin etkisi]

Luteinising hormone and follicle stimulating hormone were reduced in patients with chronic schizophrenia. Hypothalamic dopaminergic and serotonergic inputs participate in the regulation of pituitary hormones and drugs that block central dopamine and serotonin receptors are expected to influence the hypothalamus-pituitary-gonadal and hypothalamus-pituitary-adrenal axes. The trials focus on antipsychotic medications serve us critical knowledges about the pathophysiological process of schizophrenia. Results of trials on relation between schizophrenia and sexual disfunction show significant differences. Sexual dysfunction in chronic schizophrenia was related to both illness and antipsychotic treatment. Compared to treatment in the conventional antipsychotic era, patients with schizophrenic disorder taking novel antipsychotic medications now suffer less from extrapyramidal side effects. However, sexual side effects have been described as a consequence of novel antipsychotic medication as seen in conventional agents. The aim of this article is to review the effect of both schizophrenia and antipsychotics on reproductive and sexual functions