Design of Carbon Nanotube Modified Conducting Polymer for Biosensing Applications

WOS: 000291273600001An electrochemical biosensor with improved performance was designed through the immobilization of glucose oxidase (GOx) onto conducting polymer of 4-(2,5-di(thiophen-2-yl)-1H-pyrrol-1-yl)benzenamine (SNS-NH2) modified with carbon nanotubes (CNTs). For the optimization and characterization of the biosensor, pH profile, enzyme loading, reproducibility, operational stability experiments were carried out. It was found that the use of CNTs in a biosensing system enhanced the biosensor response. The linear relation was observed using glucose as the substrate in the range of 0.1-2.0 mM and defined by the equation; y = 8.582x + 2.945 (R2= 0.994, where y and x stand for concentration in mM and current signal as A/cm2). Finally, proposed biosensor was applied for glucose detection in real samples.TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [108T999]; METUMiddle East Technical University; Ege UniversityEge University; TUBATurkish Academy of SciencesThis work was supported by TUBITAK (Project number; 108T999), METU, Ege University and TUBA grants. S. Tuncagil acknowledges the scholarship obtained from TUBITAK