Psoriasis and metabolic syndrome [Psoriasis ve metabolik sendrom]

Background and Design: Psoriasis is a chronic, inflammatory disease that occurs with polygenic and other triggering factors. The association of psoriasis, which is considered to be a systemic disease, with other diseases, such as cardiovascular diseases, hepatosteatosis, obesity, diabetes mellitus, hypertension, and hyperlipidemia has been shown. Materials and Methods: In this study, we compared the levels of fasting blood glucose, serum lipid (total cholesterol, HDL cholesterol, triglyceride), basal insulin, insulin resistance and body mass index as well as cigarette and alcohol consumption in 50 adult patients with those in 50 age- and gender-matched non-psoriatic controls. Results: In our study, metabolic syndrome was present in 62% patients with psoriasis, compared with 24% of the controls (p<0,001). In psoriatic patients with metabolic syndrome PASI median value was 13,6, whereas patients without metabolic syndrome PASI median value was 11,2 and the difference was statistically significant (p