Cellular absorbed doses of Auger and conversion electrons from 111In

The purpose of this work is to calculate the microdosimetric dose distribution of the Auger and conversion electrons from 111In for both the single and cluster of cells. The total energy emitted is 32.37 keV/decay, which is the sum of Auger electron and conversion electron emission of 5.74 keV/decay and 26.63 keV/decay, respectively. The absorbed energy per decay of 111In is 5.67 keV if the chemical composition of a cell is considered. If the composition of a cell is assumed to be water, then the absorbed energy in the cell volume per decay is 3.76 keV. The absorbed dose distribution is not homogeneous, while Auger electrons deposit most of their energy within the cell, whereas conversion electrons deposit definitely less. The cluster size has little effect on the dose of the Auger electrons. However, it has a strong effect on the dose of conversion electrons. As the cluster size increases from 51 to 800 cells, the dose of conversion electrons increases by a factor of 7.8 to 14.8