Unusual sesquiterpenes from Centaurea athoa DC

WOS: 000371798400047Three new elemane-type sesquiterpenes; athoin, 14-O-acetylathoin and methyl 14-O-acetylathoin-12-oate were isolated from the aerial parts of Centaurea athoa DC., accompanying with eight known compounds: a germacrane-type sesquiterpene; 4'-hydroxypecterolide-14-O-acetate, three phenolic compounds; p-hydroxybenzoic acid, protocatechuic acid, vanillic acid-4-O-beta-D-glucopyranoside methyl ester, an acetophenon glucoside; picein, two phenylpropane glucosides; syringin and 9-O-methyl coniferin, and a phytosterol; beta-sitosterol-3-O-beta-D-glucopyranoside. Structural elucidation of the compounds was based on both spectroscopic evidence and reference data comparison. (C) 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.Scientific Research Projects Directorate of Ege UniversityEge University [12-ECZ-009]We thank Assoc. Prof. Serdar Gokhan Senol for authenticating the plant material, and Dr. Salih Gunnaz for all NMR measurements. This research project was supported by the Scientific Research Projects Directorate of Ege University (Project No: 12-ECZ-009)