Case report: A mixt episode induced by sibutramine [Sibutramin ile i·ndüklenen bir mikst epizot olgusu]

Sibutramine is an antiobesity drug which has also an inbitor effect on NE and 5HT reuptake pumps. These antidepressant pharmacodynamic properties of sibutramine has been proved by pre-clinical and clinical trials. Here, we want to report a 53 years old male patient who did not have any prior hypomanic or manic episodes had a mixed episode after a 3 months of antiobesity treatment by 30 mg/day sibutramine. Since sibutramine has an antidepressant activity drug which may cause affective or psychotic symptoms we wanted to highlight the importance of evaluating the mental and psychiatric status of patients during and prior to treatment