Aberrant placental angiogenesis is associated with fetal growth restriction (FGR). In mice, targeted disruption of the homeobox gene, transforming growth β-induced factor (Tgif-1), which is also a transcription factor, causes defective placental vascularisation. Nevertheless, the role of TGIF-1 in human placental angiogenesis is unclear. We have previously reported increased TGIF-1 expression in human FGR placentae and demonstrated localisation of TGIF-1 protein in placental endothelial cells (ECs). However, its functional role remains to be investigated. In this study, we aimed to specifically compare TGIF-1 mRNA expression in placental ECs isolated from human FGR-affected pregnancies with gestation-matched control pregnancies in two indep...
Ample interest has been evoked in using placental angiogenesis as a target for the development of di...
Objective-Biglycan (BGN) has reduced expression in placentae from pregnancies complicated by fetal g...
Objective: Vascular endothelial growth factor (VEGF) is considered the growth factor that stimulates...
Aberrant placental angiogenesis is associated with fetal growth restriction (FGR). In mice, targeted...
Aberrant placental angiogenesis is associated with fetal growth restriction (FGR). In the mouse, tar...
Fulltext embargoed for: 12 months post date of publicationAbnormal trophoblast function is associate...
AbstractThe mammalian placenta is the site of exchange of nutrients and waste between mother and emb...
Idiopathic fetal growth restriction (FGR) is frequently associated with placental insufficiency. Pre...
Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, a...
International audienceIdiopathic fetal growth restriction (FGR) is frequently associated with placen...
Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, a...
Background: Vascular endothelial growth factor (VEGF), basic-fibroblast growth factor (b-FGF), and e...
Objectives: Aberrations in placental vascular development compromising fetal supply of oxygen and es...
Fetal growth restriction (FGR) is an adverse pregnancy outcome associated with significant perinatal...
International audienceVasculogenesis and angiogenesis are key processes of placental development, wh...
Ample interest has been evoked in using placental angiogenesis as a target for the development of di...
Objective-Biglycan (BGN) has reduced expression in placentae from pregnancies complicated by fetal g...
Objective: Vascular endothelial growth factor (VEGF) is considered the growth factor that stimulates...
Aberrant placental angiogenesis is associated with fetal growth restriction (FGR). In mice, targeted...
Aberrant placental angiogenesis is associated with fetal growth restriction (FGR). In the mouse, tar...
Fulltext embargoed for: 12 months post date of publicationAbnormal trophoblast function is associate...
AbstractThe mammalian placenta is the site of exchange of nutrients and waste between mother and emb...
Idiopathic fetal growth restriction (FGR) is frequently associated with placental insufficiency. Pre...
Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, a...
International audienceIdiopathic fetal growth restriction (FGR) is frequently associated with placen...
Homeobox genes are essential for both the development of the blood and lymphatic vascular systems, a...
Background: Vascular endothelial growth factor (VEGF), basic-fibroblast growth factor (b-FGF), and e...
Objectives: Aberrations in placental vascular development compromising fetal supply of oxygen and es...
Fetal growth restriction (FGR) is an adverse pregnancy outcome associated with significant perinatal...
International audienceVasculogenesis and angiogenesis are key processes of placental development, wh...
Ample interest has been evoked in using placental angiogenesis as a target for the development of di...
Objective-Biglycan (BGN) has reduced expression in placentae from pregnancies complicated by fetal g...
Objective: Vascular endothelial growth factor (VEGF) is considered the growth factor that stimulates...