Antidepressant-discontinuation induced mania: A case report and review of the literature [Antidepresan kesilmesinin neden oldugu mani: Bir olgu ve literatürün gözden geçirilmesi]

Antidepressants have been used successfully in the treatment of depression for a long time. In the literature there are various studies and case reports about manic shift occured during antidepressant treatment. Although, it is well known that sudden discontinuation of an antidepressant drug may elicit a withdrawal reaction, mania or hypomania which can occur during sudden withdrawal of an antidepressant drug is rarely known. Recognizing this rarely known phenomenon and increasing number of in case reports will help the clinicians to predict patients who are inclined to manic shift and to understand probable etiological mechanisms. In this paper this interesting phenomenon was discussed in a case report and the literature was reviewed