Hederagenin glycosides from the flowers of Cephalaria transsylvanica

WOS: A1997WN16800012PubMed ID: 9063096Three new triterpenoidal saponins, 3-O-[beta-D-glucopyranosyl(1 -->4)-beta-D-glucopyranosyl(1-->3)-alpha-L-rhamnopyranosyl (1-->4)-beta-D-xylopyranosyl]-hederagenin 28-O-[beta-D-glucopyranosyl(1 -->4)-beta-D-glucopyranosyl] ester (1), 3-O-[beta-D-glucopyranosyl(1-->3)-alpha-L-rhamnopyranosyl(1-->2)-beta-D-xylopyranosyl]-hederagenin 28-O-[beta-D-glucopyranosyl(1-->4)-beta-D-glucopyranosyl] ester (2), and 3-O-[alpha-L-rhamnopyranosyl(1-->4)-beta-D-xylopyranosyl]-hederagenin (3) were isolated from the flowers of Cephalaria transsylvanica. Two new prosapogenins, 3-O-[beta-D-glucopyranosyl(1 -->4)-beta-D-glucopyranosyl(1-->3)-alpha-L-rhamnopyranosyl(1-->4)-beta-D-xylopyranosyl] hederagenin (4) and 3-O-[beta-D-glucopyranosyl (1-->3)-alpha-L-rhamnopyranosyl(1-->2)-beta-D-xylopyranosyl]-hederagenin (5) were also isolated after cleavage of the ester-glycosidic linkage of the bisdesmosidic compounds. Structure elucidation was carried out chemically and spectroscopically