Prognostic factors and a new prognostic index model for children and adolescents with Hodgkin’s lymphoma who underwent autologous hematopoietic stem cell transplantation: A multicenter study of the turkish pediatric bone marrow transplantation study group [Otolog hematopoetik kök hücre nakli uygulanmış Hodgkin lenfomalı çocuk ve adölesanlarda prognostik faktörler ve yeni bir prognostik indeks modeli: Türk pediatrik kemik iliği nakli çalışma grubundan çok merkezli çalışma]

PubMed ID: 27094103Objective: The prognostic factors and a new childhood prognostic index after autologous hematopoietic stem cell transplantation (AHSCT) in patients with relapsed/refractory Hodgkin’s lymphoma (HL) were evaluated. Materials and Methods: The prognostic factors of 61 patients who underwent AHSCT between January 1990 and December 2014 were evaluated. In addition, the Age-Adjusted International Prognostic Index and the Childhood International Prognostic Index (CIPI) were evaluated for their impact on prognosis. Results: The median age of the 61 patients was 14.8 years (minimum-maximum: 5-20 years) at the time of AHSCT. There were single relapses in 28 patients, ?2 relapses in eight patients, and refractory disease in 25 patients. The chemosensitivity/chemorefractory ratio was 36/25. No pretransplant radiotherapy, no remission at the time of transplantation, posttransplant white blood cell count over 10x103/ µL, posttransplant positron emission tomography positivity at day 100, and serum albumin of