Polystyrene Containing Carbinolamine/Azomethine Potentially Useful as Antimicrobial Agent: Synthesis and Biological Evaluation

WOS: 000307754600027An investigation of antimicrobial properties of 12 novel modified polymer derived from the condensation reaction of (aminomethyl)polystyrene and four substitute salicylaldehyde (2-hydroxy benzaldehyde, 5-fluoro-2 hydroxy benzaldehyde, 5-fluoro-3-chloro-salicylaldehyde and 5-fluoro-3-methyl-salicylaldehyde) has been carried out and Cr(III) and Ni(II) complexes have been prepared. Modified polymers were characterized by magnetic susceptibility, elemental analyses, and spectral studies. The H-1 NMR and C-13 NMR spectra analysis of the polymeric carbinolamine/azomethine were determined. In addition, surface morphology and composition were determined by SEM/EDX. Thermo gravimetric analyses of polymers were carried out in nitrogen atmosphere. Antibacterial activities of the polymers attached carbinolamine/azomethine and their complexes were studied by the well-diffusion method against Listeria monocytogenes 4b, Staphylococcus aureus, Escherichia coli, Salmonella typhi H, Brucella abortus, Staphylococcus epidermis sp., Micrococcus luteus, Shigella dysenteria type 10, Bacillus cereus, Pseudomonas putida and antifungal activity against Candida albicans.Gazi University Research FundGazi University [05/2010-75]; Ahi Evran UniversityAhi Evran University [FBA-11-27-2011]This work was supported by the Gazi University Research Fund (Project number: 05/2010-75) and Ahi Evran University, grant No: FBA-11-27-2011