WOS: 000338348700017PubMed: 24752352ADAMTS-2 and ADAMTS-3 (a disintegrin and metalloproteinase with thrombospondin type 1 motif 2) belong to the procollagen aminoproteinase subfamily of ADAMTS proteases. They play crucial roles in the collagen metabolism. To understand the regulation of ADAMTS-2 gene expression in osteoblastic cells, we have cloned a functional 760 bp of human ADAMTS-2 promoter. Sequence analysis of the ADAMTS-2 promoter region showed the absence of a TATA box, but identified a GC box, a CpG island, several GAGA boxes and several transcriptional factor binding sites, which may be valuable in the regulation of ADAMTS-2 transcription. We also elucidated that Interleukin 6 (IL-6) increases ADAMTS-2 and ADAMTS-3 mRNA and protei...
We previously reported that matrix metalloproteinase (MMP)-10 mRNA levels were significantly lower i...
Objective: To examine the expression of ADAMTS-7 during the progression of osteoarthritis (OA), defi...
Zhong Wu,* Weizhi Yang,* Junjian Liu, Fan Zhang Department of Orthopedics, Shanghai Tenth People&rs...
WOS: 000433015400001PubMed: 29518549ADAMTS3 is a member of procollagen N-proteinase subfamily of ADA...
© 2015 Kelwick et al.The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enz...
WOS: 000362305000018PubMed: 26232334Up-regulation of ADAMTS genes with proinflammatory cytokines is ...
The ADAMTS proteinases are a group of multidomain and secreted metalloproteinases containing the thr...
The human ADAMTS (a disintegrin and metalloproteinase with thrombospondin-like motifs) family of 19 ...
ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin motifs), the first described membe...
Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are kn...
A Disintegrin-like And Metalloproteinase with ThromboSpondin motifs—ADAMTSs—are a multi-domain, secr...
ADAMTS (A disintegrin and metalloproteinase with thrombospondin motifs)-like (ADAMTSL) proteins, a s...
The a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family of metalloproteas...
ADAMTSs are a family of secreted proteinases that share the metalloproteinase domain with matrix met...
Nuclear factor-B (NF-B) is involved in the regulation of inflammation-associated genes. NF-B forms d...
We previously reported that matrix metalloproteinase (MMP)-10 mRNA levels were significantly lower i...
Objective: To examine the expression of ADAMTS-7 during the progression of osteoarthritis (OA), defi...
Zhong Wu,* Weizhi Yang,* Junjian Liu, Fan Zhang Department of Orthopedics, Shanghai Tenth People&rs...
WOS: 000433015400001PubMed: 29518549ADAMTS3 is a member of procollagen N-proteinase subfamily of ADA...
© 2015 Kelwick et al.The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enz...
WOS: 000362305000018PubMed: 26232334Up-regulation of ADAMTS genes with proinflammatory cytokines is ...
The ADAMTS proteinases are a group of multidomain and secreted metalloproteinases containing the thr...
The human ADAMTS (a disintegrin and metalloproteinase with thrombospondin-like motifs) family of 19 ...
ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin motifs), the first described membe...
Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are kn...
A Disintegrin-like And Metalloproteinase with ThromboSpondin motifs—ADAMTSs—are a multi-domain, secr...
ADAMTS (A disintegrin and metalloproteinase with thrombospondin motifs)-like (ADAMTSL) proteins, a s...
The a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family of metalloproteas...
ADAMTSs are a family of secreted proteinases that share the metalloproteinase domain with matrix met...
Nuclear factor-B (NF-B) is involved in the regulation of inflammation-associated genes. NF-B forms d...
We previously reported that matrix metalloproteinase (MMP)-10 mRNA levels were significantly lower i...
Objective: To examine the expression of ADAMTS-7 during the progression of osteoarthritis (OA), defi...
Zhong Wu,* Weizhi Yang,* Junjian Liu, Fan Zhang Department of Orthopedics, Shanghai Tenth People&rs...