In this article, we propose an investigation of the modifications of the hydrological response of two Peruvian Amazonas-Andes basins in relationship with the modifications of the precipitation and evapotranspiration rates inferred by the IPCC. These two basins integrate around 10% of the total area of the Amazonian basin. These estimations are based on the application of two monthly hydrological models, GR2M and MWB3, and the climatic projections come from BCM2, CSMK3 and MIHR models for A1B and B1 emission scenarios (SCE A1B and SCE B1). Projections are approximated by two simple scenarios (anomalies and horizon) and annual rainfall rates, evapotranspiration rates and discharge were estimated for the 2020s (2008-2040), 2050s (2041-2070) an...