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Not AvailableFish processing and preservation is mainly concerned with improving the quality and value of seafood and one of the most reliable methods for maintaining the quality of fish is to keep them alive till consumption. This guarantees freshness and more consumer demand unlike the other processed commodities. However the stress associated with the live fish handling and transportation is a major challenge and minimizing this can successfully improve the survival rate and associated biochemical quality changes of the fish. Anaesthetics are known for reducing stress and related problems during live fish transportation. Hence, a study was carried out to understand the efficacy of anaesthetics viz., MS 222, AQUI-S and clove essential oil on the survival of common tilapia (Oreochromis mossambicus). Results indicated that these sedatives had differential effect on live tilapia, with distinctly diverse induction and recovery time as well rate of survival. Among the three anaesthetics used, highest dosage was required for MS 222, moderate levels for AQUIS and lowest for essential oil for the same extent of sedation in live tilapia. However more intense studies are required to understand the dosage levels for long term transportation. Similarly toxicological studies on the use of essential oil are to be intensely explored to standardize their permissible concentrations in food fishes. Further, trials on the individual and combined effect of low temperature and aeration conditions on the survival rate of live tilapia proved, temperature and aeration to play a significant role in influencing the survival of tilapia.Not Availabl