International audiencePurpose: To determine the plasma metabolomic signature of primary open-angle glaucoma (POAG).Methods: We compared the metabolomic profiles of plasma from individuals with POAG (n = 36) with age- and sex-matched controls with cataract (n = 27). A targeted metabolomics study was performed using the standardized p180 Biocrates Absolute IDQ p180 kit with a QTRAP 5500 mass spectrometer. Multivariate analyses were performed using principal component analysis (PCA) and the least absolute shrinkage and selection operator (LASSO) method.Results: Among the 151 metabolites accurately measured, combined univariate and multivariate analyses revealed 18 discriminant metabolites belonging to the carbohydrate, acyl-carnitine, phosphat...
ABSTARCT:Glaucoma is a chronic disease that shares many similarities with other neurodegenerative di...
Glaucoma is a chronic disease that shares many similarities with other neurodegenerative disorders o...
<div><p>Primary open angle glaucoma (POAG) is a multi-factorial optic disc neuropathy characterized ...
Purpose: To determine the plasma metabolomic signature of primary open-angle glaucoma (POAG). Method...
We compared the metabolomic profile of aqueous humor from patients with primary open-angle glaucoma ...
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the select...
Glaucoma is an insidious group of eye diseases causing degeneration of the optic nerve, progressive ...
Glaucoma is still a poorly understood disease with a clear need for new biomarkers to help in diagno...
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the select...
We compared the metabolomic profile of aqueous humor from patients with primary open-angle glaucoma ...
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the select...
Age-related macular degeneration (AMD) is a common, progressive multifactorial vision-threatening di...
Age-related macular degeneration (AMD) is a common, progressive multifactorial vision-threatening di...
The composition of the aqueous humor of patients with glaucoma is relevant to understand the underly...
Glaucoma related proteomic changes have been documented in cell and animal models. However, proteomi...
ABSTARCT:Glaucoma is a chronic disease that shares many similarities with other neurodegenerative di...
Glaucoma is a chronic disease that shares many similarities with other neurodegenerative disorders o...
<div><p>Primary open angle glaucoma (POAG) is a multi-factorial optic disc neuropathy characterized ...
Purpose: To determine the plasma metabolomic signature of primary open-angle glaucoma (POAG). Method...
We compared the metabolomic profile of aqueous humor from patients with primary open-angle glaucoma ...
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the select...
Glaucoma is an insidious group of eye diseases causing degeneration of the optic nerve, progressive ...
Glaucoma is still a poorly understood disease with a clear need for new biomarkers to help in diagno...
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the select...
We compared the metabolomic profile of aqueous humor from patients with primary open-angle glaucoma ...
Primary Open Angle Glaucoma (POAG) is a common neurodegenerative disease characterized by the select...
Age-related macular degeneration (AMD) is a common, progressive multifactorial vision-threatening di...
Age-related macular degeneration (AMD) is a common, progressive multifactorial vision-threatening di...
The composition of the aqueous humor of patients with glaucoma is relevant to understand the underly...
Glaucoma related proteomic changes have been documented in cell and animal models. However, proteomi...
ABSTARCT:Glaucoma is a chronic disease that shares many similarities with other neurodegenerative di...
Glaucoma is a chronic disease that shares many similarities with other neurodegenerative disorders o...
<div><p>Primary open angle glaucoma (POAG) is a multi-factorial optic disc neuropathy characterized ...