International audienceCystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR (cystic fibrosis transmembrane conductance regulator) gene mutations. CF is characterized by an ionic imbalance and thickened mucus, which impair mucociliary clearance and promote bacterial colonization and the establishment of infection/inflammation cycles. However, the origin of this inflammation remains unclear, although microRNAs (miRNAs) are suspected to be involved. MiRNAs are small non-coding RNAs that bind to the 3'-untranslated regions (UTRs) of target gene mRNA, thereby repressing their translation and/or inducing their degradation. The goal of this study was to investigate the role of microRNAs associated with pulmonary inflammati...
MicroRNAs (miRs) have emerged as major regulators of the protein content of a cell. In the most part...
Since the demonstration that microRNAs are deeply involved in the regulation of Cystic Fibrosis (CF)...
International audienceThe CFTR gene displays a tightly regulated tissue-specific and temporal expres...
International audienceCystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR...
In patients with cystic fibrosis (CF), at the pulmonary level, the ionic imbalance caused by CFTR ch...
International audienceCystic fibrosis (CF) results from deficient CF transmembrane conductance regul...
Cystic Fibrosis (CF) is due to mutation in the chloride channel CFTR gene causing impairment of chlo...
Cystic fibrosis (CF) is due to mutations in the chloride channel CFTR gene causing impairment of chl...
La mucoviscidose (CF pour Cystic Fibrosis) est la conséquence de mutations du gène codant pour le ca...
As essential components of the regulatory system of gene expression, microRNAs (miRNAs) have been sh...
MicroRNAs (miRNAs) are small non-coding RNAs involved in regulation of gene expression. They bind in...
MicroRNAs (miRNAs) have recently emerged as important gene regulators in Cystic Fibrosis (CF), a com...
The cystic fibrosis lung is a complex milieu comprising multiple factors that coordinate its physiol...
International audienceCystic fibrosis (CF), a genetic disorder, is characterized by chronic lung dis...
Interleukin (IL)-8 levels are higher than normal in cystic fibrosis (CF) airways, causing neutrophil...
MicroRNAs (miRs) have emerged as major regulators of the protein content of a cell. In the most part...
Since the demonstration that microRNAs are deeply involved in the regulation of Cystic Fibrosis (CF)...
International audienceThe CFTR gene displays a tightly regulated tissue-specific and temporal expres...
International audienceCystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR...
In patients with cystic fibrosis (CF), at the pulmonary level, the ionic imbalance caused by CFTR ch...
International audienceCystic fibrosis (CF) results from deficient CF transmembrane conductance regul...
Cystic Fibrosis (CF) is due to mutation in the chloride channel CFTR gene causing impairment of chlo...
Cystic fibrosis (CF) is due to mutations in the chloride channel CFTR gene causing impairment of chl...
La mucoviscidose (CF pour Cystic Fibrosis) est la conséquence de mutations du gène codant pour le ca...
As essential components of the regulatory system of gene expression, microRNAs (miRNAs) have been sh...
MicroRNAs (miRNAs) are small non-coding RNAs involved in regulation of gene expression. They bind in...
MicroRNAs (miRNAs) have recently emerged as important gene regulators in Cystic Fibrosis (CF), a com...
The cystic fibrosis lung is a complex milieu comprising multiple factors that coordinate its physiol...
International audienceCystic fibrosis (CF), a genetic disorder, is characterized by chronic lung dis...
Interleukin (IL)-8 levels are higher than normal in cystic fibrosis (CF) airways, causing neutrophil...
MicroRNAs (miRs) have emerged as major regulators of the protein content of a cell. In the most part...
Since the demonstration that microRNAs are deeply involved in the regulation of Cystic Fibrosis (CF)...
International audienceThe CFTR gene displays a tightly regulated tissue-specific and temporal expres...