Alternative splicing profiling of Aire-sensitive genes in the thymic epithelium revealed increased splice event exclusion

Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus

Guyon, Clotilde
Jmari, Nada
Padonou, Francine
Li, Yen-Chin
Ucar, Olga
Fujikado, Noriyuki
Coulpier, Fanny
Blanchet, Christophe
Root, David
Giraud, Matthieu

April 2020

International audienceThe ability of the immune system to avoid autoimmune disease relies on toleriz...

Identification of alternative-splicing events in human monocyte differentiation

Sim, Donald Yuhui

January 2018

The alternative splicing of precursor messenger RNA is an important determinant of gene expression a...

Identification of a novel cis-regulatory element essential for immune tolerance

Laflam, Taylor N.
Seumois, Grégory
Miller, Corey N.
Lwin, Wint
Fasano, Kayla J.
Waterfield, Michael
Proekt, Irina
Vijayanand, Pandurangan
Anderson, Mark S.

November 2015

Thymic central tolerance is essential to preventing autoimmunity. In medullary thymic epithelial cel...

Alternative splicing profiling of Aire-sensitive genes in the thymic epithelium revealed increased splice event exclusion

Padonou, F.
Gonzalez, V.
Jmari, N.
Saare, M.
Allanore, Y.
Peterson, P.
Irla, M.
Giraud, M.

January 2019

17th International Congress of Immunology (IUIS), Beijing, PEOPLES R CHINA, OCT 19-23, 201

Promiscuous mrna splicing under the control of aire in medullary thymic epithelial cells

Keane, Peter
Ceredig, Rhodri
Seoighe, Cathal

September 2018

Motivation: The expression of tissue-restricted antigens (TRAs) in the thymus is required to ensure ...

Alternative splicing profiling of Aire induced-genes in the thymus

Padonou, Abogundé Francine

July 2020

Les cellules médullaires épithéliales thymiques (mTEC), sous l'effet de la protéine Aire sont capabl...

A transcriptomics-based investigation of the landscape and mechanisms of self-antigen splicing in thymic epithelial cells

Jansen, K

January 2019

Thymic epithelial cells (TEC) are remarkable for their ability to promiscuously express virtually th...

Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells

Danan-Gotthold, Miri
Guyon, Clotilde
Giraud, Matthieu
Levanon, Erez, y
Abramson, Jakub

October 2016

International audienceBackground: In order to become functionally competent but harmless mediators o...

Differential splicing across immune system lineages.

Ergun, Ayla
Doran, Graeme
Costello, James C
Paik, Henry H
Collins, James J
Mathis, Diane
Benoist, Christophe
ImmGen Consortium

August 2013

Alternative splicing (AS) allows increased diversity and orthogonal regulation of the transcriptiona...

RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus

Jansen, Kathrin
Shikama-Dorn, Noriko
Attar, Moustafa
Maio, Stefano
Lopopolo, Maria
Buck, David
Holländer, Georg A.
Sansom, Stephen N.

November 2021

Thymic epithelial cells (TEC) control the selection of a T cell repertoire reactive to pathogens but...

Differential splicing across immune system lineages

Ergun, Ayla
Doran, Graeme
Costello, James
Paik, Henry
Collins, James
Mathis, Diane
Mathis, Diane
Benoist, Christophe
Benoist, Christophe
Blair, David
Dustin, Michael
Shinton, Susan
Hardy, Richard
Shay, Tal
Regevc, Aviv
Cohen, Nadia
Brennan, Patrick
Brenner, Michael
Kim, Francis
Nageswara Rao, Tata
Wagers, Amy
Heng, Tracy
Ericson, Jeffrey
Rothamel, Katherine
Ortiz-Lopez, Adriana
Kreslavsky, Taras
Fletcher, Anne
Elpek, Kutlu
Bellemare-Pelletier, Angelique
Malhotra, Deepali
Turley, Shannon
Miller, Jennifer
Brown, Brian
Merad, Miriam
Gautier, Emmanuel
Jakubzick, Claudia
Randolph, Gwendalyn
Monach, Paul
Best, Adam
Knell, Jamie
Goldrath, Ananda
Jojic, Vladimir
Koller, Daphne
Laidlaw, David
Collins, Jim
Gazit, Roi
Rossi, Derrick
Malhotra, Nidhi
Sylvia, Katelyn
Kang, Joonsoo
Bezman, Natalie
Sun, Joseph
Min-Oo, Gundula
Kim, Charlie
Lanier, Lewis

August 2013

International audienceAlternative splicing (AS) allows increased diversity and orthogonal regulation...

Global analysis of alternative splicing in human cells of myeloid origin

Lorenzini Paolo Alberto

January 2018

Pre-mRNA splicing is one of the processing steps by which the genetic information flows in a biologi...

Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

Toyoshi Yanagihara
Fumiyuki Sanematsu
Tetsuya Sato
Takehito Uruno
Xuefeng Duan
Takahiro Tomino
Yosuke Harada
Mayuki Watanabe
Yuqing Wang
Yoshihiko Tanaka
Yoichi Nakanishi
Mikita Suyama
Fukui Yoshinori

August 2016

The thymus has spatially distinct microenvironments, the cortex and the medulla, where the developin...

Identification of a novel cis-regulatory element essential for immune tolerance.

LaFlam, Taylor N
Seumois, Grégory
Miller, Corey N
Lwin, Wint
Fasano, Kayla J
Waterfield, Michael
Proekt, Irina
Vijayanand, Pandurangan
Anderson, Mark S

November 2015

Thymic central tolerance is essential to preventing autoimmunity. In medullary thymic epithelial cel...

Aire controls gene expression in the thymic epithelium with ordered stochasticity

Meredith, Matthew
Zemmour, David
Mathis, Diane
Benoist, Christophe

April 2016

Aire controls immunologic tolerance by inducing the ectopic thymic expression of many tissue-specifi...

Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus

Guyon, Clotilde
Jmari, Nada
Padonou, Francine
Li, Yen-Chin
Ucar, Olga
Fujikado, Noriyuki
Coulpier, Fanny
Blanchet, Christophe
Root, David
Giraud, Matthieu

April 2020

International audienceThe ability of the immune system to avoid autoimmune disease relies on toleriz...

Identification of alternative-splicing events in human monocyte differentiation

Sim, Donald Yuhui

January 2018

The alternative splicing of precursor messenger RNA is an important determinant of gene expression a...

Identification of a novel cis-regulatory element essential for immune tolerance

Laflam, Taylor N.
Seumois, Grégory
Miller, Corey N.
Lwin, Wint
Fasano, Kayla J.
Waterfield, Michael
Proekt, Irina
Vijayanand, Pandurangan
Anderson, Mark S.

November 2015

Thymic central tolerance is essential to preventing autoimmunity. In medullary thymic epithelial cel...

Alternative splicing profiling of Aire-sensitive genes in the thymic epithelium revealed increased splice event exclusion

Padonou, F.
Gonzalez, V.
Jmari, N.
Saare, M.
Allanore, Y.
Peterson, P.
Irla, M.
Giraud, M.

January 2019

17th International Congress of Immunology (IUIS), Beijing, PEOPLES R CHINA, OCT 19-23, 201

Promiscuous mrna splicing under the control of aire in medullary thymic epithelial cells

Keane, Peter
Ceredig, Rhodri
Seoighe, Cathal

September 2018

Motivation: The expression of tissue-restricted antigens (TRAs) in the thymus is required to ensure ...

Alternative splicing profiling of Aire induced-genes in the thymus

Padonou, Abogundé Francine

July 2020

Les cellules médullaires épithéliales thymiques (mTEC), sous l'effet de la protéine Aire sont capabl...

A transcriptomics-based investigation of the landscape and mechanisms of self-antigen splicing in thymic epithelial cells

Jansen, K

January 2019

Thymic epithelial cells (TEC) are remarkable for their ability to promiscuously express virtually th...

Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells

Danan-Gotthold, Miri
Guyon, Clotilde
Giraud, Matthieu
Levanon, Erez, y
Abramson, Jakub

October 2016

International audienceBackground: In order to become functionally competent but harmless mediators o...

Differential splicing across immune system lineages.

Ergun, Ayla
Doran, Graeme
Costello, James C
Paik, Henry H
Collins, James J
Mathis, Diane
Benoist, Christophe
ImmGen Consortium

August 2013

Alternative splicing (AS) allows increased diversity and orthogonal regulation of the transcriptiona...

RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus

Jansen, Kathrin
Shikama-Dorn, Noriko
Attar, Moustafa
Maio, Stefano
Lopopolo, Maria
Buck, David
Holländer, Georg A.
Sansom, Stephen N.

November 2021

Thymic epithelial cells (TEC) control the selection of a T cell repertoire reactive to pathogens but...

Differential splicing across immune system lineages

Ergun, Ayla
Doran, Graeme
Costello, James
Paik, Henry
Collins, James
Mathis, Diane
Mathis, Diane
Benoist, Christophe
Benoist, Christophe
Blair, David
Dustin, Michael
Shinton, Susan
Hardy, Richard
Shay, Tal
Regevc, Aviv
Cohen, Nadia
Brennan, Patrick
Brenner, Michael
Kim, Francis
Nageswara Rao, Tata
Wagers, Amy
Heng, Tracy
Ericson, Jeffrey
Rothamel, Katherine
Ortiz-Lopez, Adriana
Kreslavsky, Taras
Fletcher, Anne
Elpek, Kutlu
Bellemare-Pelletier, Angelique
Malhotra, Deepali
Turley, Shannon
Miller, Jennifer
Brown, Brian
Merad, Miriam
Gautier, Emmanuel
Jakubzick, Claudia
Randolph, Gwendalyn
Monach, Paul
Best, Adam
Knell, Jamie
Goldrath, Ananda
Jojic, Vladimir
Koller, Daphne
Laidlaw, David
Collins, Jim
Gazit, Roi
Rossi, Derrick
Malhotra, Nidhi
Sylvia, Katelyn
Kang, Joonsoo
Bezman, Natalie
Sun, Joseph
Min-Oo, Gundula
Kim, Charlie
Lanier, Lewis

August 2013

International audienceAlternative splicing (AS) allows increased diversity and orthogonal regulation...

Global analysis of alternative splicing in human cells of myeloid origin

Lorenzini Paolo Alberto

January 2018

Pre-mRNA splicing is one of the processing steps by which the genetic information flows in a biologi...

Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus

Toyoshi Yanagihara
Fumiyuki Sanematsu
Tetsuya Sato
Takehito Uruno
Xuefeng Duan
Takahiro Tomino
Yosuke Harada
Mayuki Watanabe
Yuqing Wang
Yoshihiko Tanaka
Yoichi Nakanishi
Mikita Suyama
Fukui Yoshinori

August 2016

The thymus has spatially distinct microenvironments, the cortex and the medulla, where the developin...

Identification of a novel cis-regulatory element essential for immune tolerance.

LaFlam, Taylor N
Seumois, Grégory
Miller, Corey N
Lwin, Wint
Fasano, Kayla J
Waterfield, Michael
Proekt, Irina
Vijayanand, Pandurangan
Anderson, Mark S

November 2015

Thymic central tolerance is essential to preventing autoimmunity. In medullary thymic epithelial cel...

Aire controls gene expression in the thymic epithelium with ordered stochasticity

Meredith, Matthew
Zemmour, David
Mathis, Diane
Benoist, Christophe

April 2016

Aire controls immunologic tolerance by inducing the ectopic thymic expression of many tissue-specifi...

Aire-dependent genes undergo Clp1-mediated 3'UTR shortening associated with higher transcript stability in the thymus

Guyon, Clotilde
Jmari, Nada
Padonou, Francine
Li, Yen-Chin
Ucar, Olga
Fujikado, Noriyuki
Coulpier, Fanny
Blanchet, Christophe
Root, David
Giraud, Matthieu

April 2020

International audienceThe ability of the immune system to avoid autoimmune disease relies on toleriz...

Identification of alternative-splicing events in human monocyte differentiation

Sim, Donald Yuhui

January 2018

The alternative splicing of precursor messenger RNA is an important determinant of gene expression a...

Identification of a novel cis-regulatory element essential for immune tolerance

Laflam, Taylor N.
Seumois, Grégory
Miller, Corey N.
Lwin, Wint
Fasano, Kayla J.
Waterfield, Michael
Proekt, Irina
Vijayanand, Pandurangan
Anderson, Mark S.

November 2015

Thymic central tolerance is essential to preventing autoimmunity. In medullary thymic epithelial cel...

Alternative splicing profiling of Aire-sensitive genes in the thymic epithelium revealed increased splice event exclusion

Abstract

Extracted data

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