Background: Impairment of apoptosis is a hallmark of cancer. Tumor resistance to apoptosis usually caused by deregulation of the expression of BCL-2 family protein or mutation of the tumor suppressor gene p53. Over expression of Bcl-2 is commonly found in various types of cancer including breast cancer. Studies mentioned that analysis of Bcl-2 might predict response to selected endocrine and chemotherapies. Purpose: Evaluation of correlation of BCL-2 mRNA expression and clinical response to neoadjuvant chemotherapy in breast cancer patients. Method: longitudinal study, 30 subjects of breast cancer tissue samples prechemotherapy using cyclophosphamide-adriamycin-5FU regiment. Detection of mRNA expression of BCL-2 using qRT-PCR techniques
The proto-oncogene bcl-2 encodes a protein that inhibits apoptosis, a common mechanism of cell death...
Invasive Ductal carcinoma is the most common histological type of breast cancer. It constitutes abou...
AbstractContext: Breast cancer treatment has experienced several changes in the last decades due to ...
Impairment of apoptosis is a hallmark of cancer. Tumor resistance to apoptosis usually caused by der...
-Impairment of apoptosis is a hallmark of cancer. Tumor resistance to apoptosis usually caused by de...
The change in expression of apoptotic markers (Bcl-2 and Bax proteins) brought about by various chem...
Background: Cancer is one of the major human problems and breast cancer is a significant health prob...
PURPOSE: Bcl-2 and p53 are known to act as a regulator of apoptosis in breast cancer and we evaluate...
We have analyzed the predictive/prognostic value of Bcl-2 protein in breast cancer patients treated ...
Journal Scopus Q3 PrihantonoBackground and Objective: Estrogen Receptor (ER) expression promotes the...
Purpose: The purpose was to evaluate the utility of some bcl-2 family proteins fas and fasL as predi...
The proto-oncogene bcl-2 encodes a protein that inhibits apoptosis, a common mechanism of cell death...
Bcl-2 is an anti-apoptotic protein belonging to a family of proteins that act as regulators of apopt...
Although the status of the axillary lymph nodes is widely accepted to be associated with prognosis i...
Background: TNBC represents a heterogeneous subgroup of BC with poor prognosis and frequently resist...
The proto-oncogene bcl-2 encodes a protein that inhibits apoptosis, a common mechanism of cell death...
Invasive Ductal carcinoma is the most common histological type of breast cancer. It constitutes abou...
AbstractContext: Breast cancer treatment has experienced several changes in the last decades due to ...
Impairment of apoptosis is a hallmark of cancer. Tumor resistance to apoptosis usually caused by der...
-Impairment of apoptosis is a hallmark of cancer. Tumor resistance to apoptosis usually caused by de...
The change in expression of apoptotic markers (Bcl-2 and Bax proteins) brought about by various chem...
Background: Cancer is one of the major human problems and breast cancer is a significant health prob...
PURPOSE: Bcl-2 and p53 are known to act as a regulator of apoptosis in breast cancer and we evaluate...
We have analyzed the predictive/prognostic value of Bcl-2 protein in breast cancer patients treated ...
Journal Scopus Q3 PrihantonoBackground and Objective: Estrogen Receptor (ER) expression promotes the...
Purpose: The purpose was to evaluate the utility of some bcl-2 family proteins fas and fasL as predi...
The proto-oncogene bcl-2 encodes a protein that inhibits apoptosis, a common mechanism of cell death...
Bcl-2 is an anti-apoptotic protein belonging to a family of proteins that act as regulators of apopt...
Although the status of the axillary lymph nodes is widely accepted to be associated with prognosis i...
Background: TNBC represents a heterogeneous subgroup of BC with poor prognosis and frequently resist...
The proto-oncogene bcl-2 encodes a protein that inhibits apoptosis, a common mechanism of cell death...
Invasive Ductal carcinoma is the most common histological type of breast cancer. It constitutes abou...
AbstractContext: Breast cancer treatment has experienced several changes in the last decades due to ...