THE HEAMODYNAMIC RESPONSE TO THE CRUDE AQUEOUS EXTRACT OF CRINUM MACOWANII BULBS (CAEB) IN ANAESTHETIZED WISTAR RATS

Crinum macowanii is used in traditional medicine. To increase efficacy and safety we evaluated the haemodynamic effect of the CAEB. CAEB was administered via the jugular vein after sodium pentobarbitone anaesthesia (40 mg/kg, i.p.) and tracheostomy. The rats were placed on a heating pad at 37ºC. A Powerlab© using Deltran II© pressure transducers monitored femoral arterial pressure (BP). The heart rate (HR) was determined from BP. The data is reported as mean±SD (n=6) with significance set at