Influenza virus surveillance in Argentina during the 2012 season: Antigenic characterization, genetic analysis and antiviral susceptibility
- Benedetti, Estefanía
- Daniels , R. S.
- Pontoriero, Andrea
- Russo, M. L.
- Avaro, Martin
- Czech, Andrea
- Campos, Ana
- Periolo, Natalia
- Gregory, V.
- McCauley, J.W.
- Baumeister, Elsa
DOIAbstract
The activity and circulation of influenza viruses in Argentina was studied during 2012 as part of the Argentinean Surveillance for Influenza and other Respiratory Viruses, in the context of Global Influenza Surveillance. The antigenicity and molecular characteristics of haemagglutinins (HA) of circulating influenza A and B viruses were analysed to assess the emergence of virus variants. Susceptibility to oseltamivir and zanamivir was evaluated by enzymatic assay and results were backed-up by sequencing of the neuraminidase (NA) genes. During the 2012 season, influenza virus circulation in Argentina was detected from weeks 24 to 51. The HA sequences of the studied A(H1N1)pdm09 subtype viruses segregated in a different genetic group compared ...
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