Add to ORKGthis article, we develop a similar Quantitative Pedigree Disequilibrium Test (QPDT) to test for linkage and association in general pedigrees for quantitative traits. We apply both the PDT and the QPDT to analyze the sequence data from the seven candidate genes in the simulated data sets in the 12 Genetic Analysis Worksho
[[abstract]]This chapter considers allelic association to be association occurring between alleles a...
We use likelihood-based score statistics to test for association between a disease and a diallelic p...
We considered a strategy to map quantitative trait loci (QTLs) using linkage disequilibrium (LD) whe...
Family-based tests of linkage disequilibrium typically are based on nuclear-family data including af...
Association mapping based on family studies can identify genes that influence complex human traits w...
SummaryThe transmission/disequilibrium (TD) test (TDT), proposed, by Spielman et al., for binary tra...
The transmission disequilibrium test (TDT) has been utilized to test the linkage and association bet...
We develop a score statistic to test for linkage in the presence of linkage disequilibrium for quant...
International audienceABSTRACT : We used Genetic Analysis Workshop 16 Problem 3 Framingham Heart Stu...
We used Genetic Analysis Workshop 16 Problem 3 Framingham Heart Study simulated data set to compare ...
Recently, the use of linkage disequilibrium (LD) to locate genes which affect quantitative traits (Q...
SummaryHigh-resolution mapping is an important step in the identification of complex disease genes. ...
SummaryThe transmission/disequilibrium test (TDT) developed by Spielman et al. can be a powerful fam...
SummaryLinkage disequilibrium (LD) mapping can be successful if there is strong nonrandom associatio...
Because of the need for fine mapping of disease loci and the availability of dense single-nucleotide...
[[abstract]]This chapter considers allelic association to be association occurring between alleles a...
We use likelihood-based score statistics to test for association between a disease and a diallelic p...
We considered a strategy to map quantitative trait loci (QTLs) using linkage disequilibrium (LD) whe...
Family-based tests of linkage disequilibrium typically are based on nuclear-family data including af...
Association mapping based on family studies can identify genes that influence complex human traits w...
SummaryThe transmission/disequilibrium (TD) test (TDT), proposed, by Spielman et al., for binary tra...
The transmission disequilibrium test (TDT) has been utilized to test the linkage and association bet...
We develop a score statistic to test for linkage in the presence of linkage disequilibrium for quant...
International audienceABSTRACT : We used Genetic Analysis Workshop 16 Problem 3 Framingham Heart Stu...
We used Genetic Analysis Workshop 16 Problem 3 Framingham Heart Study simulated data set to compare ...
Recently, the use of linkage disequilibrium (LD) to locate genes which affect quantitative traits (Q...
SummaryHigh-resolution mapping is an important step in the identification of complex disease genes. ...
SummaryThe transmission/disequilibrium test (TDT) developed by Spielman et al. can be a powerful fam...
SummaryLinkage disequilibrium (LD) mapping can be successful if there is strong nonrandom associatio...
Because of the need for fine mapping of disease loci and the availability of dense single-nucleotide...
[[abstract]]This chapter considers allelic association to be association occurring between alleles a...
We use likelihood-based score statistics to test for association between a disease and a diallelic p...
We considered a strategy to map quantitative trait loci (QTLs) using linkage disequilibrium (LD) whe...