IOS Press DNA computing approach to semantic

Abstract. DNA computing has a lot of potential, in terms of ability to implement a relational database with circular molecules. In this work, a new DNA-based semantic model is proposed and described theoretically for implementing DNA based memories. This model, referred to as ‘semantic model based on molecular computing ’ (SMC), has the structure of a graph formed by the set of all attribute-value pairs contained in the set of represented objects, plus a tag node for each object. Each path in the network, from an initial object-representing tag node to a terminal node represents the object named on the tag. Input of a set of input strands will result in the formation of object-representing dsDNAs via parallel self-assembly, from encoded ssDNAs representing (value, attribute)-pairs (nodes), as directed by ssDNA splinting strands representing relations (edges) in the network. The computational complexity of the implementation is estimated via simple simulation, which indicates the advantage of the approach over a sequential model. We believe that the semantic models are rather suitable for DNA-based memory, and that this proposal is the first such approach in the semantic networks area. 1