Abstract. It is not known how membrane fusion proteins that function at neutral pH, for example the human immunodeficiency virus envelope (Env) glycoprotein and intracellular fusion machines, are activated for target bilayer binding. We have addressed this question using a soluble oligomeric form of an avian retroviral Env glycoprotein (API) and soluble forms of its receptor. Binding of soluble receptor to API induces API to bind to liposomes composed of phosphatidylcholine and cholesterol at neutral pH. Liposome binding only occurs at fusion permissive temperatures (T � 20�C), is complete between 2 to 5 min at 37�C, and is stable to high salt, carbonate, and urea. Liposome binding is mediate
Enveloped viruses require fusion between the viral envelope and the target membrane for entry into ...
The retroviral structural protein Gag is the primary driving force of assembly of retroviruses. Gag ...
Many phleboviruses (family Bunyaviridae) are emerging, medically important viruses. These viruses en...
It is not known how membrane fusion proteins that function at neutral pH, for example the human immu...
The fusion of lipid bilayers is central to a number of diverse processes, such as fertilization, syn...
The retrovirus, avian sarcoma and leukosis virus (ASLV), enters cells through a pH-independent fusio...
Semliki Forest virus (SFV) has been shown previously to fuse efficiently with cholesterol-and sphing...
Semliki Forest virus (SFV) has been shown previously to fuse efficiently with cholesterol-and sphing...
AbstractSemliki Forest virus (SFV) has been shown previously to fuse efficiently with cholesterol- a...
AbstractMembrane fusion of enveloped viruses with cellular membranes is mediated by viral glycoprote...
e 6 (Marsh and Helenius, 2006). In the low pH-independent pathway, it is proposed that virus glycopr...
Assembly of an infectious retroviral particle relies on multimerization of the Gag polyprotein at th...
There is controversy as to whether the cell entry mechanism of Sindbis virus (SIN) involves direct f...
International audienceEnveloped viruses penetrate their cell targets following the merging of their ...
Cellular entry of Ebola virus (EBOV), a deadly hemorrhagic fever virus, is mediated by the viral gly...
Enveloped viruses require fusion between the viral envelope and the target membrane for entry into ...
The retroviral structural protein Gag is the primary driving force of assembly of retroviruses. Gag ...
Many phleboviruses (family Bunyaviridae) are emerging, medically important viruses. These viruses en...
It is not known how membrane fusion proteins that function at neutral pH, for example the human immu...
The fusion of lipid bilayers is central to a number of diverse processes, such as fertilization, syn...
The retrovirus, avian sarcoma and leukosis virus (ASLV), enters cells through a pH-independent fusio...
Semliki Forest virus (SFV) has been shown previously to fuse efficiently with cholesterol-and sphing...
Semliki Forest virus (SFV) has been shown previously to fuse efficiently with cholesterol-and sphing...
AbstractSemliki Forest virus (SFV) has been shown previously to fuse efficiently with cholesterol- a...
AbstractMembrane fusion of enveloped viruses with cellular membranes is mediated by viral glycoprote...
e 6 (Marsh and Helenius, 2006). In the low pH-independent pathway, it is proposed that virus glycopr...
Assembly of an infectious retroviral particle relies on multimerization of the Gag polyprotein at th...
There is controversy as to whether the cell entry mechanism of Sindbis virus (SIN) involves direct f...
International audienceEnveloped viruses penetrate their cell targets following the merging of their ...
Cellular entry of Ebola virus (EBOV), a deadly hemorrhagic fever virus, is mediated by the viral gly...
Enveloped viruses require fusion between the viral envelope and the target membrane for entry into ...
The retroviral structural protein Gag is the primary driving force of assembly of retroviruses. Gag ...
Many phleboviruses (family Bunyaviridae) are emerging, medically important viruses. These viruses en...