Investigation of Approaches for the Localization of Anatomical Landmarks

We investigate the extraction of corresponding anatomical point landmarks in MR and CT images of the human head using 3D di erential operators for the extraction of isocontour curvature extrema. We carried out experiments measuring the sensitivity to noise, the localization accuracy, the false detection rate and the registration accuracy. Based on the experimental results we compare the performance of six di erent approaches. 1