Inference and adaptation in noisy and changing, rich sensory environments are rife with a variety of specific sorts of variability. Experimental and theoretical studies suggest that these different forms of variability play different behavioral, neural and computational roles, and may be reported by different (notably neuromodulatory) systems. Here, we refine our previous theory of acetylcholine’s role in cortical inference in the (oxymoronic) terms of expected uncertainty, and advocate a theory for norepinephrine in terms of unexpected uncertainty. We suggest that norepinephrine reports the radical divergence of bottom-up inputs from prevailing top-down interpretations, to influence inference and plasticity. We illustrate this proposal usi...
Acetylcholine (ACh) plays an important role in a wide variety of cognitive tasks, such as perception...
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under unc...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Inference and adaptation in noisy and changing, rich sensory environ-ments are rife with a variety o...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
SummaryUncertainty in various forms plagues our interactions with the environment. In a Bayesian sta...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Classical and instrumental conditioning paradigms pose animals elemental (though not always elementa...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
A rich body of experimental data indicates that the neuromodulatory systems acetylcholine (ACh) and ...
In order to deal with the uncertainty in the world, our brains need to be able to flexibly switch be...
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under unc...
We build models of the world around us to guide perception and learning in the face of uncertainty. ...
Acetylcholine (ACh) plays an important role in a wide variety of cognitive tasks, such as perception...
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under unc...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Inference and adaptation in noisy and changing, rich sensory environ-ments are rife with a variety o...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
SummaryUncertainty in various forms plagues our interactions with the environment. In a Bayesian sta...
Uncertainty in various forms plagues our interactions with the environment. In a Bayesian statistica...
Classical and instrumental conditioning paradigms pose animals elemental (though not always elementa...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...
A rich body of experimental data indicates that the neuromodulatory systems acetylcholine (ACh) and ...
In order to deal with the uncertainty in the world, our brains need to be able to flexibly switch be...
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under unc...
We build models of the world around us to guide perception and learning in the face of uncertainty. ...
Acetylcholine (ACh) plays an important role in a wide variety of cognitive tasks, such as perception...
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under unc...
Successful interaction with the environment requires flexible updating of our beliefs about the worl...