Add to ORKGthis reporter to rapamycin. Construction of an additional control plasmid demonstrated, however, that these sequences did not confer any detectable sensitivity to rapamycin (our unpublished results). Taken together, these results demonstrate that rapamycin affects r-protein gene expression at the level of transcriptio
The mTOR inhibitor rapamycin has anti-tumor activity across a variety of human cancers, including he...
Polysomal messenger RNA (mRNA) populations change rapidly in response to alterations in the physiolo...
mTORC1 (mammalian target of rapamycin complex 1) is controlled by diverse signals (e.g. hormones, gr...
<p>The effect of rapamycin on GPx-1 activity (A) and protein levels (B) in KU812a, MEG-01 GM10832 or...
Polysomal messenger RNA (mRNA) populations change rapidly in response to alterations in the physiolo...
Abstract Background Recent work, using both cell culture model systems and tumour derived cell lines...
BACKGROUND: We investigated mTOR regulation of gene expression by studying rapamycin effect in two h...
We investigated mTOR regulation of gene expression by studying rapamycin effect in two hepatic cell ...
<p>Messenger ORF50 RNA and RTA protein levels were assessed in BCBL-1 pre-treated with rapamycin for...
<p>Rapamycin was added to HUVECs at concentrations of 2, 20, 200 and 2000 ng/ml for 24 and 48 hours....
<p>(A) Kinetics of the effect of rapamycin on mTORC1 activity. 293 cells were amino acid-starved for...
<p>After stimulation with thrombin for 4 hours, HUVECs were treated with rapamycin at final concentr...
<p><b>A)</b> Growth assay; Sen1 wild-type, Sen1-1 and Sen1-2 strains were grown at 30°C to log-phase...
Rapamycin is a macrolide antibiotic that functions as an immunosuppressive and anti-cancer agent, an...
Rapamycin is a potent cytostatic agent that arrests cells in the G1 phase of the cell cycle. The rel...
The mTOR inhibitor rapamycin has anti-tumor activity across a variety of human cancers, including he...
Polysomal messenger RNA (mRNA) populations change rapidly in response to alterations in the physiolo...
mTORC1 (mammalian target of rapamycin complex 1) is controlled by diverse signals (e.g. hormones, gr...
<p>The effect of rapamycin on GPx-1 activity (A) and protein levels (B) in KU812a, MEG-01 GM10832 or...
Polysomal messenger RNA (mRNA) populations change rapidly in response to alterations in the physiolo...
Abstract Background Recent work, using both cell culture model systems and tumour derived cell lines...
BACKGROUND: We investigated mTOR regulation of gene expression by studying rapamycin effect in two h...
We investigated mTOR regulation of gene expression by studying rapamycin effect in two hepatic cell ...
<p>Messenger ORF50 RNA and RTA protein levels were assessed in BCBL-1 pre-treated with rapamycin for...
<p>Rapamycin was added to HUVECs at concentrations of 2, 20, 200 and 2000 ng/ml for 24 and 48 hours....
<p>(A) Kinetics of the effect of rapamycin on mTORC1 activity. 293 cells were amino acid-starved for...
<p>After stimulation with thrombin for 4 hours, HUVECs were treated with rapamycin at final concentr...
<p><b>A)</b> Growth assay; Sen1 wild-type, Sen1-1 and Sen1-2 strains were grown at 30°C to log-phase...
Rapamycin is a macrolide antibiotic that functions as an immunosuppressive and anti-cancer agent, an...
Rapamycin is a potent cytostatic agent that arrests cells in the G1 phase of the cell cycle. The rel...
The mTOR inhibitor rapamycin has anti-tumor activity across a variety of human cancers, including he...
Polysomal messenger RNA (mRNA) populations change rapidly in response to alterations in the physiolo...
mTORC1 (mammalian target of rapamycin complex 1) is controlled by diverse signals (e.g. hormones, gr...