We investigate theoretically a novel mechanism of transducing chemical energy into a directed force. A hypothetical motor protein is considered such that conformational changes induced by nucleotide binding and/or hydrolysis lead to asymmetric internal velocity fluctuations. We demonstrate that these fluctuations result in unidirectional motion if rectified by protein friction. The motor protein force-velocity relationship and other characteristics are computed based on analogy with known molecular motors. ---------------------------------------------------------------------------- -------------------- PACS 05.40, 82.20M Key words: brownian ratchet; molecular motors; protein friction. -------------------------------------------------------...
We show that the correlated stochastic fluctuation of the friction coefficient can give rise to long...
The “asymmetric Brownian ratchet model”, a variation of Feynman’s ratchet and pawl system, is invoke...
Although molecular motors of various kinds have been proposed during the last decade to try to expla...
Abstract.Motor proteins are enzymes that convert chemical energy derived from the hydrolysis of ATP ...
AbstractInteraction between a protein and a series of binding sites on a cytoskeletal substrate can ...
AbstractInteraction between a protein and a series of binding sites on a cytoskeletal substrate can ...
Motor proteins are microscopic biological machines that convert chemical energy into mechanical moti...
Motor proteins are microscopic biological machines that convert chemical energy into mechanical moti...
The typical biochemical paradigm for coupling between hydrolysis of ATP and the performance of chemi...
AbstractKinesin and nonclaret disjunctional protein (ncd) are two microtubule-based molecular motors...
A stochastic model for the action of motor proteins such as kinesin is presented. The mechanical com...
Several classes of biological molecules that transform chemical energy into mechanical work are know...
xii, 112 p. : ill. (some col.)Biological molecular motors exist in an interesting regime of physics ...
We implement a model to represent the effect of the deformation of the backbone of a system of motor...
Although molecular motors of various kinds have been proposed during the last decade to try to expla...
We show that the correlated stochastic fluctuation of the friction coefficient can give rise to long...
The “asymmetric Brownian ratchet model”, a variation of Feynman’s ratchet and pawl system, is invoke...
Although molecular motors of various kinds have been proposed during the last decade to try to expla...
Abstract.Motor proteins are enzymes that convert chemical energy derived from the hydrolysis of ATP ...
AbstractInteraction between a protein and a series of binding sites on a cytoskeletal substrate can ...
AbstractInteraction between a protein and a series of binding sites on a cytoskeletal substrate can ...
Motor proteins are microscopic biological machines that convert chemical energy into mechanical moti...
Motor proteins are microscopic biological machines that convert chemical energy into mechanical moti...
The typical biochemical paradigm for coupling between hydrolysis of ATP and the performance of chemi...
AbstractKinesin and nonclaret disjunctional protein (ncd) are two microtubule-based molecular motors...
A stochastic model for the action of motor proteins such as kinesin is presented. The mechanical com...
Several classes of biological molecules that transform chemical energy into mechanical work are know...
xii, 112 p. : ill. (some col.)Biological molecular motors exist in an interesting regime of physics ...
We implement a model to represent the effect of the deformation of the backbone of a system of motor...
Although molecular motors of various kinds have been proposed during the last decade to try to expla...
We show that the correlated stochastic fluctuation of the friction coefficient can give rise to long...
The “asymmetric Brownian ratchet model”, a variation of Feynman’s ratchet and pawl system, is invoke...
Although molecular motors of various kinds have been proposed during the last decade to try to expla...