Poster CATALYTIC APPLICATION OF MESOPOROUS SILICAS IN SYNTHESIS OF SUBSTITUTED IMIDAZOLES UNDER MICROWAVE IRRADIATION AND SOLVENT- FREE

Mesoporus compounds, founded in 1992, are of great interest because of their remarkable properties, such as their large surface area and pore volume, narrow pore size distribution, and the ease with which their surface can be functionalized. There are many applications for these compounds namely hard template for nanopowder synthesis [1], molecular sieves [2], catalysis[3] and catalyst support [4]. Microwave-assisted rapid organic reactions, on the other hand, constitute an emerging technology, that make organic syntheses more effective and more eco-friendly than conventional reactions. Microwave-assisted synthesis of heterocyclic compounds is also being attended in combinatorial chemistry synthesis of fine chemicals and pharmaceuticals. This report is focused on application of this technique for environmentally friendly synthesis of substituted imidazoles using SBA-15 mesoporous silica as an efficient catalyst. Some of tri and tetra substituted imidazoles have been known for several years in agrochemicals as herbicide, fungicide [5-6], and also in photography as photosensitive compound [7]. Moreover, compounds with the imidazole ring system have many pharmacological properties and play important roles in biochemical processes.In addition imidazole is the basic skeletal o