This thesis will be about trying to find out which paths evolution took for some selected small organisms and about the influence of backward mutations on a genetic landscape. We will take a look at empirical data and also find features of the models that we use to understand them. Therefore it is important to know about epistasis, which we will treat here as the influence of one mutation on the effect of another. This definition is different from a lot of other definitions that exist for this term (see also [1])
Fitness interactions between mutations can influence a population’s evolution in many different ways...
The fitness effect of mutations can be influenced by their interactions with the environment, other ...
Fitness interactions between mutations can influence a population's evolution in many different ways...
Epistatic interactions between mutations add substantial complexity to adaptive landscapes, and are ...
Unraveling the factors that determine the rate of adaptation is a major question in evolutionary bio...
Evolutionary accessibility quantifies the likelihood of reaching favorable states within fitness lan...
A combinatorially complete data set consists of studies of all possible combinations of a set of mut...
Background: Understanding interactions between mutations and how they affect fitness is a central pr...
Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. As...
Mutations are the source of evolutionary variation. The interactions of multiple mutations can have ...
Epistasis occurs when the effect of a mutation depends on its carrier's genetic background. Despite ...
Along with being consequential for evolution, epistasis is also quite prevalent in nature. Thus, it ...
International audienceThe fitness landscapethe mapping between genotypes and fitnessdetermines prope...
How do the fitness effects of several mutations combine? Despite its simplicity, this question is ce...
<div><p>Evolutionary pathways describe trajectories of biological evolution in the space of differen...
Fitness interactions between mutations can influence a population’s evolution in many different ways...
The fitness effect of mutations can be influenced by their interactions with the environment, other ...
Fitness interactions between mutations can influence a population's evolution in many different ways...
Epistatic interactions between mutations add substantial complexity to adaptive landscapes, and are ...
Unraveling the factors that determine the rate of adaptation is a major question in evolutionary bio...
Evolutionary accessibility quantifies the likelihood of reaching favorable states within fitness lan...
A combinatorially complete data set consists of studies of all possible combinations of a set of mut...
Background: Understanding interactions between mutations and how they affect fitness is a central pr...
Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. As...
Mutations are the source of evolutionary variation. The interactions of multiple mutations can have ...
Epistasis occurs when the effect of a mutation depends on its carrier's genetic background. Despite ...
Along with being consequential for evolution, epistasis is also quite prevalent in nature. Thus, it ...
International audienceThe fitness landscapethe mapping between genotypes and fitnessdetermines prope...
How do the fitness effects of several mutations combine? Despite its simplicity, this question is ce...
<div><p>Evolutionary pathways describe trajectories of biological evolution in the space of differen...
Fitness interactions between mutations can influence a population’s evolution in many different ways...
The fitness effect of mutations can be influenced by their interactions with the environment, other ...
Fitness interactions between mutations can influence a population's evolution in many different ways...