Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM increases with age, and younger age-at-diagnosis is significantly associated with improved prognosis. While the relationship between candidate GBM risk SNPs and age-at-diagnosis has been explored, genome-wide association studies (GWAS) have not previously been stratified by age. Potential age-specific genetic effects were assessed in autosomal SNPs for GBM patients using data from four previous GWAS. Using age distribution tertiles (18-53, 54-64, 65+) datasets were analyzed using age-stratified logistic regression to generate p values, odds ratios (OR), and 95% confidence intervals (95%CI), and then combined using meta-analysis. There were 4,5...
To identify risk variants for glioma, we conducted a meta-analysis of two genome-wide association st...
Glioblastoma multiforme (GBM) is the most common and aggressive primary central nervous system malig...
BACKGROUND: Although recent sequencing studies have revealed that 10% of childhood gliomas are cause...
Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM i...
Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM i...
Since the first reports in 2009, genome-wide association studies (GWAS) have been successful in iden...
Age is a powerful predictor of survival in glioblastoma multiforme (GBM) yet the biological basis fo...
Previous genome-wide association studies (GWASs) have shown that common genetic variation contribute...
Genome-wide association studies (GWAS) have so far identified 25 loci associated with glioma risk, w...
Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, ...
Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, ...
Genome-wide association studies (GWAS) have successfully identified a number of common single-nucleo...
BackgroundGlioblastomas are the most common primary brain tumour in adults. While the prognosis for ...
To identify risk variants for glioma, we conducted a meta-analysis of two genome-wide association st...
Glioblastoma multiforme (GBM) is the most common and aggressive primary central nervous system malig...
BACKGROUND: Although recent sequencing studies have revealed that 10% of childhood gliomas are cause...
Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM i...
Glioblastoma (GBM) is the most common malignant brain tumor in the United States. Incidence of GBM i...
Since the first reports in 2009, genome-wide association studies (GWAS) have been successful in iden...
Age is a powerful predictor of survival in glioblastoma multiforme (GBM) yet the biological basis fo...
Previous genome-wide association studies (GWASs) have shown that common genetic variation contribute...
Genome-wide association studies (GWAS) have so far identified 25 loci associated with glioma risk, w...
Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, ...
Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, ...
Genome-wide association studies (GWAS) have successfully identified a number of common single-nucleo...
BackgroundGlioblastomas are the most common primary brain tumour in adults. While the prognosis for ...
To identify risk variants for glioma, we conducted a meta-analysis of two genome-wide association st...
Glioblastoma multiforme (GBM) is the most common and aggressive primary central nervous system malig...
BACKGROUND: Although recent sequencing studies have revealed that 10% of childhood gliomas are cause...