There is no standard of care in the UK or Ireland for second-line chemotherapy for patients with advanced transitional cell carcinoma (TCCU). Vinflunine is approved for TCCU patients who have failed a platinum-based regimen, and is standard of care in Europe but is not routinely available in the UK. Data were collected retrospectively on patients who received vinfluine as a second-line treatment. The aims were to document the toxicity and efficacy in a real life setting. Data were collected on 49 patients from 9 sites across the UK and Ireland [median age, 64 (IQR, 57-70) years, 33 males]. All patients had advanced metastatic TCCU. Thirteen patients had bone or liver metastases, 4 patients had PS 2 and 11 patients had HB <10. Median vinflun...
BACKGROUND:Despite the advent of immunotherapy in urothelial cancer, there is still a need to find e...
Vinflunine is the only cytotoxic agent tested as a second line therapy in transitional cell carcinom...
Objective. There is the second generalized analysis of administration of vinflunine in real clinical...
There is no standard of care in the UK or Ireland for second-line chemotherapy for patients with adv...
BackgroundA systematic review and meta-analysis of the use of systemic vinflunine (VIN) in the treat...
Background. Vinflunine (VFL) is approved in Europe as second-line treatment of metastatic urothelial...
Maintenance therapy improves outcomes in various tumour types, but cumulative toxic effects limit th...
Background Vinflunine is recommended in the European guideline for the treatment of advanced or met...
Abstract Background Vinflunine is the only chemotherapeutic agent shown to improve survival in plati...
Objective: to assess safety, responses rate and duration, progression-free and overall survival in p...
Introduction: Vinflunine is a microtubule inhibitor approved in Europe as second-line treatment of a...
Background: Vinflunine is a microtubule inhibitor of the vinca alkaloid class approved for the treat...
Advanced urothelial cancer (UC) is an aggressive disease with high morbidity and mortality. The prim...
BACKGROUND: The activity and safety of vinflunine was evaluated in patients with locally advanced or...
Background: There is no standard first-line chemotherapy for advanced urothelial carcinoma (aUC) in...
BACKGROUND:Despite the advent of immunotherapy in urothelial cancer, there is still a need to find e...
Vinflunine is the only cytotoxic agent tested as a second line therapy in transitional cell carcinom...
Objective. There is the second generalized analysis of administration of vinflunine in real clinical...
There is no standard of care in the UK or Ireland for second-line chemotherapy for patients with adv...
BackgroundA systematic review and meta-analysis of the use of systemic vinflunine (VIN) in the treat...
Background. Vinflunine (VFL) is approved in Europe as second-line treatment of metastatic urothelial...
Maintenance therapy improves outcomes in various tumour types, but cumulative toxic effects limit th...
Background Vinflunine is recommended in the European guideline for the treatment of advanced or met...
Abstract Background Vinflunine is the only chemotherapeutic agent shown to improve survival in plati...
Objective: to assess safety, responses rate and duration, progression-free and overall survival in p...
Introduction: Vinflunine is a microtubule inhibitor approved in Europe as second-line treatment of a...
Background: Vinflunine is a microtubule inhibitor of the vinca alkaloid class approved for the treat...
Advanced urothelial cancer (UC) is an aggressive disease with high morbidity and mortality. The prim...
BACKGROUND: The activity and safety of vinflunine was evaluated in patients with locally advanced or...
Background: There is no standard first-line chemotherapy for advanced urothelial carcinoma (aUC) in...
BACKGROUND:Despite the advent of immunotherapy in urothelial cancer, there is still a need to find e...
Vinflunine is the only cytotoxic agent tested as a second line therapy in transitional cell carcinom...
Objective. There is the second generalized analysis of administration of vinflunine in real clinical...