Contains fulltext : 208980.pdf (publisher's version ) (Open Access
Coronary heart disease (CHD) is a significant cause of morbidity and mortality worldwide. Many risk ...
Before biomarker discoveries can be commercially utilized in clinical laboratories, many studies and...
CONTEXT: Prior studies have demonstrated conflicting results regarding how much information novel bi...
Background: Translating prognostic and diagnostic biomarker candidates into clinical applications ta...
The last decade has seen an extraordinary amount of effort devoted in biomedical research to the fie...
Biomarkers are becoming an essential part of clinical development, not least because they offer a fa...
Many promising biomarkers for stratifying individuals at risk of developing a chronic disease or sub...
Despite considerable research investment, moving from biomarker discovery to clinical application ha...
The majority of day-to-day clinical decision making is guided by the laboratory measurement of a bio...
This thesis consists of four chapters: an introductory chapter and three research papers on specific...
Treatment selection based on average effects observed in entire target population masks variation am...
Objectives: Individuals are often prioritised for preventive cardiovascular disease (CVD) therapy b...
We study the incentives of drug producers to develop predictive biomarkers, taking into account stra...
This paper examines incentives for pharmaceutical firms to invest in biomarkers that predict which g...
Discovery of novel biomarkers and improvement of risk predic-tion algorithms will be a key to fulfil...
Coronary heart disease (CHD) is a significant cause of morbidity and mortality worldwide. Many risk ...
Before biomarker discoveries can be commercially utilized in clinical laboratories, many studies and...
CONTEXT: Prior studies have demonstrated conflicting results regarding how much information novel bi...
Background: Translating prognostic and diagnostic biomarker candidates into clinical applications ta...
The last decade has seen an extraordinary amount of effort devoted in biomedical research to the fie...
Biomarkers are becoming an essential part of clinical development, not least because they offer a fa...
Many promising biomarkers for stratifying individuals at risk of developing a chronic disease or sub...
Despite considerable research investment, moving from biomarker discovery to clinical application ha...
The majority of day-to-day clinical decision making is guided by the laboratory measurement of a bio...
This thesis consists of four chapters: an introductory chapter and three research papers on specific...
Treatment selection based on average effects observed in entire target population masks variation am...
Objectives: Individuals are often prioritised for preventive cardiovascular disease (CVD) therapy b...
We study the incentives of drug producers to develop predictive biomarkers, taking into account stra...
This paper examines incentives for pharmaceutical firms to invest in biomarkers that predict which g...
Discovery of novel biomarkers and improvement of risk predic-tion algorithms will be a key to fulfil...
Coronary heart disease (CHD) is a significant cause of morbidity and mortality worldwide. Many risk ...
Before biomarker discoveries can be commercially utilized in clinical laboratories, many studies and...
CONTEXT: Prior studies have demonstrated conflicting results regarding how much information novel bi...