Modular Design of Small Enzymatic Reaction Networks Based on Reversible and Cleavable Inhibitors

Learning to design resistance proof drugs from folding

R. A. Broglia

April 2008

Learning how proteins fold will hardly have any impact on the way conventional — active site centere...

From Enzymatic Reaction Networks Towards Synthetic Metabolic Pathways

Helwig, B.

January 2021

Contains fulltext : 238536.pdf (Publisher’s version ) (Open Access)Radboud Univers...

A computational method for design of connected catalytic networks in proteins

Weitzner, Brian D.
Kipnis, Yakov
Daniel, A. Gerard
Hilvert, Donald
Baker, David

December 2019

Computational design of new active sites has generally proceeded by geometrically defining interacti...

Rational design of enzymatic reaction networks

Postma, S.G.J.

January 2018

Contains fulltext : 183332.pdf (publisher's version ) (Open Access)Radboud Univers...

Molecular engineering of enzymatic reaction networks

Pogodaev, A.

January 2021

Contains fulltext : 228316.pdf (publisher's version ) (Open Access)Radboud Univers...

Rational design of functional and tunable oscillating enzymatic networks

Semenov, S.N.
Wong, A.S.Y.
Made, R.M. van der
Postma, S.G.J.
Groen, J.
Roekel, H.W.H. van
Greef, T.F.A. de
Huck, W.T.S.

January 2015

Contains fulltext : 140116.pdf (publisher's version ) (Closed access

Bottom-Up Construction of an Adaptive Enzymatic Reaction Network

Helwig, Britta
Sluijs, Bob van
Pogodaev, A.
Postma, S.G.J.
Huck, Wilhelm T.S.

January 2018

Contains fulltext : 197203.pdf (Publisher’s version ) (Open Access

A Compartmentalized Out-of-Equilibrium Enzymatic Reaction Network for Sustained Autonomous Movement

Nijemeisland, M.
Abdelmohsen, L.K.E.A.
Huck, W.T.S.
Wilson, D.A.
Hest, J. van

January 2016

Contains fulltext : 166222.pdf (publisher's version ) (Open Access

Figure 1. Structure-guided design of zinc-complexed AB3 teramer (Zn8:AB34) A Designed Supramolecular Protein Assembly with in-Vivo Enzymatic Activity

January 2015

A major goal in molecular design and engineering is the creation of new enzymes from scratch. Howeve...

Preprogramming complex hydrogel responses using enzymatic reaction networks

Postma, S.G.J.
Vialshin, I.
Gerritsen, C.Y.
Bao, M.
Huck, W.T.S.

January 2017

Contains fulltext : 169079.pdf (Publisher’s version ) (Open Access

Grip on complexity in chemical reaction networks

Wong, A.S.Y.
Huck, W.T.S.

January 2017

Contains fulltext : 177749.pdf (publisher's version ) (Open Access

Testing the Substrate-Envelope Hypothesis with Designed Pairs of Compounds

Tariq M. Rana
Celia A. Schiffer
Bruce Tidor

August 2016

ABSTRACT: Acquired resistance to therapeutic agents is a significant barrier to the development of c...

Testing the substrate-envelope hypothesis with designed pairs of compounds

Shen, Yang
Altman, Michael D.
Ali, Akbar
Nalam, Madhavi N. L.
Cao, Hong
Rana, Tariq M.
Schiffer, Celia A.
Tidor, Bruce

November 2013

Acquired resistance to therapeutic agents is a significant barrier to the development of clinically ...

A rational blueprint for the design of chemically-controlled protein switches

Shui, Sailan
Gainza, Pablo
Scheller, Leo
Yang, Che
Kurumida, Yoichi
Rosset, Stéphane
Georgeon, Sandrine
Di Roberto, Raphaël B.
Castellanos-Rueda, Rocío
Reddy, Sai T.
Correia, Bruno E.

October 2021

Small-molecule responsive protein switches are crucial components to control synthetic cellular acti...

Minimal cut sets in biochemical reaction networks

Klamt, S.
Gilles, E.

January 2004

Motivation: Structural studies of metabolic networks yield deeper insight into topology, functionali...

Learning to design resistance proof drugs from folding

R. A. Broglia

April 2008

Learning how proteins fold will hardly have any impact on the way conventional — active site centere...

From Enzymatic Reaction Networks Towards Synthetic Metabolic Pathways

Helwig, B.

January 2021

Contains fulltext : 238536.pdf (Publisher’s version ) (Open Access)Radboud Univers...

A computational method for design of connected catalytic networks in proteins

Weitzner, Brian D.
Kipnis, Yakov
Daniel, A. Gerard
Hilvert, Donald
Baker, David

December 2019

Computational design of new active sites has generally proceeded by geometrically defining interacti...

Rational design of enzymatic reaction networks

Postma, S.G.J.

January 2018

Contains fulltext : 183332.pdf (publisher's version ) (Open Access)Radboud Univers...

Molecular engineering of enzymatic reaction networks

Pogodaev, A.

January 2021

Contains fulltext : 228316.pdf (publisher's version ) (Open Access)Radboud Univers...

Rational design of functional and tunable oscillating enzymatic networks

Semenov, S.N.
Wong, A.S.Y.
Made, R.M. van der
Postma, S.G.J.
Groen, J.
Roekel, H.W.H. van
Greef, T.F.A. de
Huck, W.T.S.

January 2015

Contains fulltext : 140116.pdf (publisher's version ) (Closed access

Bottom-Up Construction of an Adaptive Enzymatic Reaction Network

Helwig, Britta
Sluijs, Bob van
Pogodaev, A.
Postma, S.G.J.
Huck, Wilhelm T.S.

January 2018

Contains fulltext : 197203.pdf (Publisher’s version ) (Open Access

A Compartmentalized Out-of-Equilibrium Enzymatic Reaction Network for Sustained Autonomous Movement

Nijemeisland, M.
Abdelmohsen, L.K.E.A.
Huck, W.T.S.
Wilson, D.A.
Hest, J. van

January 2016

Contains fulltext : 166222.pdf (publisher's version ) (Open Access

Figure 1. Structure-guided design of zinc-complexed AB3 teramer (Zn8:AB34) A Designed Supramolecular Protein Assembly with in-Vivo Enzymatic Activity

January 2015

A major goal in molecular design and engineering is the creation of new enzymes from scratch. Howeve...

Preprogramming complex hydrogel responses using enzymatic reaction networks

Postma, S.G.J.
Vialshin, I.
Gerritsen, C.Y.
Bao, M.
Huck, W.T.S.

January 2017

Contains fulltext : 169079.pdf (Publisher’s version ) (Open Access

Grip on complexity in chemical reaction networks

Wong, A.S.Y.
Huck, W.T.S.

January 2017

Contains fulltext : 177749.pdf (publisher's version ) (Open Access

Testing the Substrate-Envelope Hypothesis with Designed Pairs of Compounds

Tariq M. Rana
Celia A. Schiffer
Bruce Tidor

August 2016

ABSTRACT: Acquired resistance to therapeutic agents is a significant barrier to the development of c...

Testing the substrate-envelope hypothesis with designed pairs of compounds

Shen, Yang
Altman, Michael D.
Ali, Akbar
Nalam, Madhavi N. L.
Cao, Hong
Rana, Tariq M.
Schiffer, Celia A.
Tidor, Bruce

November 2013

Acquired resistance to therapeutic agents is a significant barrier to the development of clinically ...

A rational blueprint for the design of chemically-controlled protein switches

Shui, Sailan
Gainza, Pablo
Scheller, Leo
Yang, Che
Kurumida, Yoichi
Rosset, Stéphane
Georgeon, Sandrine
Di Roberto, Raphaël B.
Castellanos-Rueda, Rocío
Reddy, Sai T.
Correia, Bruno E.

October 2021

Small-molecule responsive protein switches are crucial components to control synthetic cellular acti...

Minimal cut sets in biochemical reaction networks

Klamt, S.
Gilles, E.

January 2004

Motivation: Structural studies of metabolic networks yield deeper insight into topology, functionali...

Learning to design resistance proof drugs from folding

R. A. Broglia

April 2008

Learning how proteins fold will hardly have any impact on the way conventional — active site centere...

From Enzymatic Reaction Networks Towards Synthetic Metabolic Pathways

Helwig, B.

January 2021

Contains fulltext : 238536.pdf (Publisher’s version ) (Open Access)Radboud Univers...

A computational method for design of connected catalytic networks in proteins

Weitzner, Brian D.
Kipnis, Yakov
Daniel, A. Gerard
Hilvert, Donald
Baker, David

December 2019

Computational design of new active sites has generally proceeded by geometrically defining interacti...

Modular Design of Small Enzymatic Reaction Networks Based on Reversible and Cleavable Inhibitors

Abstract

Extracted data

Modular Design of Small Enzymatic Reaction Networks Based on Reversible and Cleavable Inhibitors

Abstract

Extracted data

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