Lipase-Catalyzed Interesterification for the Synthesis of Medium-Long-Medium (MLM) Structured Lipids – A Review

Strukturirani lipidi građeni od srednje- i dugolančanih masnih kiselina obično imaju srednjelančane masne kiseline (C6-C12) na poziciji sn-1,3 i dugolančane masne kiseline (C14-C24) na poziciji sn-2. Imaju smanjenu kalorijsku vrijednost i pogodni su za kontrolu pretilosti te sprečavanje malapsorpcije masti i ostalih metaboličkih poremećaja. U fokusu ovog revijalnog prikaza je sinteza lipida iz srednje- i dugolančanih masnih kiselina pomoću enzimske esterifikacije. Obuhvaća detaljan opis biokatalizatora, podloga, reaktora i postupaka sinteze, te raspravu o primjeni tih lipida u proizvodnji prehrambenih proizvoda. Podaci u ovom radu daju pregled trenutnog stanja u području razvoja postupaka sinteze strukturiranih lipida iz srednje- i dugolančanih masnih kiselina.Medium-long-medium (MLM) structured lipids typically contain medium-chain fatty acids (C6-C12) at sn-1,3 and long-chain fatty acids (C14-C24) at sn-2 positions. They have reduced calories and are suitable for the control of obesity, lipid malabsorption and other metabolic disorders. This review focuses on the synthesis of MLM lipids by the enzymatic interesterification. It gives detailed description of biocatalysts, substrates, reactors and synthesis methods, and discusses the use of MLM lipids in food products. The information provided in this review can be considered as the current state-of-the art for developing a future strategy for the synthesis of MLM structured lipids