Add to ORKGA versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tertiary allylic amines has been developed. The vinyl bromide used to control enantioselectivity in a preceding CBS reduction is utilized as a synthetic handle for the preparation of tertiary α-amino ketones and related derivatives in an asymmetric fashion
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
A synthetic approach to the heterodimeric bisindole alkaloid leucophyllidine is disclosed herein. An...
The first nickel-catalyzed enantioselective allylic alkylation of lactone and lactam substrates to d...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
Herein, we report the first Pd‐catalyzed enantioselective arylation of α‐substituted γ‐lactams. Two ...
The enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted α-h...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
The first total synthesis of the norcembranoid diterpenoid scabrolide A is disclosed. The route begi...
Tetrahydrobenzo[b]azepines (THBAs) are commonly found in many bioactive compounds; however, the modu...
We report the palladium-catalyzed asymmetric allylic alkylation of 1,4-diazepan-5-ones. This reactio...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
A synthetic approach to the heterodimeric bisindole alkaloid leucophyllidine is disclosed herein. An...
The first nickel-catalyzed enantioselective allylic alkylation of lactone and lactam substrates to d...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
A versatile thermal Overman rearrangement of enantioenriched, cyclic allylic alcohols providing tert...
Herein, we report the first Pd‐catalyzed enantioselective arylation of α‐substituted γ‐lactams. Two ...
The enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted α-h...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
Herein, we report the palladium-catalyzed decarboxylative asymmetric allylic alkylation of α-enamino...
The first total synthesis of the norcembranoid diterpenoid scabrolide A is disclosed. The route begi...
Tetrahydrobenzo[b]azepines (THBAs) are commonly found in many bioactive compounds; however, the modu...
We report the palladium-catalyzed asymmetric allylic alkylation of 1,4-diazepan-5-ones. This reactio...
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substitut...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
In this report, we establish that a readily available nickel/bis(oxazoline) catalyst accomplishes a ...
A synthetic approach to the heterodimeric bisindole alkaloid leucophyllidine is disclosed herein. An...
The first nickel-catalyzed enantioselective allylic alkylation of lactone and lactam substrates to d...