Early detection of chronic asymptomatic chagas infection
- de la Rosa, Ezequiel
- Paglini Oliva, Patricia
- Prato, Laura Beatriz
- Triquell, María Fernanda
- Benizio, Evangelina Leticia
- Muñoz, Sonia Edith
- Fernandez, Elmer Andres
DOIAbstract
Chagas disease, also known as American trypanosomiasis, is a chronic and systemic parasitic infection which has become a serious epidemiological problem not only in endemic regions (Latin America), but also in nonendemic ones like North America, Europe, and Oceania. Subjects with the indeterminate chagasic form (ICF), a chronic asymptomatic disease stage, are the main sources of non-vectorial dissemination through blood transfusion, organ transplantation, and congenital transmission. It has been suggested that 94% of urban infections can be explained by these subjects. Under this scenario, the availability of simple and effective screening methods for ICF detection becomes crucial for both prevention of disease propagation and detection of ...
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