Zebrafish (Danio rerio) is emerging as an important model to understand the cellular basis of epilepsy and cognitive impairment and for treatment screening. This has led to the development of new methods for the identification, quantification and classification of epileptiform events independently from the classic visual scoring of activity. In our laboratory we exploited the availability of a non-pigmented zebrafish expressing the Ca2+ sensor GCaMP6f in neurons to demonstrate the quantitative evaluation of activity and recruitment of neuronal populations by combining local field potential recordings (LFP) with simultaneous two-photon calcium imaging. We have implemented an automated data pipeline which, through machine learning methods, ha...
Zebrafish epilepsy models are emerging tools in experimental epilepsy. Zebrafish larvae, in particul...
Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Althou...
This dataset contains all functional calcium imaging datasets of larval zebrafish acute seizure mode...
Epilepsy is a neurological disorder characterized by recurrent spontaneous burst of synchronized act...
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these network...
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these network...
Conventionally, epileptic seizures are detected and characterized in zebrafish either as behavioral ...
BACKGROUND: Epilepsy is a chronic neurological condition, with over 30% of cases unresponsive to tre...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
Summary: STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disa...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, a...
STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, a...
Zebrafish epilepsy models are emerging tools in experimental epilepsy. Zebrafish larvae, in particul...
Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Althou...
This dataset contains all functional calcium imaging datasets of larval zebrafish acute seizure mode...
Epilepsy is a neurological disorder characterized by recurrent spontaneous burst of synchronized act...
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these network...
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these network...
Conventionally, epileptic seizures are detected and characterized in zebrafish either as behavioral ...
BACKGROUND: Epilepsy is a chronic neurological condition, with over 30% of cases unresponsive to tre...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
Summary: STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disa...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
Mapping neuronal activity during the onset and propagation of epileptic seizures can provide a bette...
STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, a...
STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, a...
Zebrafish epilepsy models are emerging tools in experimental epilepsy. Zebrafish larvae, in particul...
Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Althou...
This dataset contains all functional calcium imaging datasets of larval zebrafish acute seizure mode...