This paper deals with the reconstruction of a Proto-Tupí derivation process by which names of object would be derived from transitive verbs by means of a prefix **-mi-, whose resulting form would have been combined with a marker for mediated possession **-e(p)-. This proposal, developed according to the Historical Comparative Method, is supported by data from seven of the ten families which constitute the Tupí linguistic stock. KEYWORDS: Historical Linguistics. Linguistic reconstruction. Nominalization. Mediated possession. Morphosyntax . Tupí linguistic stock.Apresentamos uma proposta de reconstrução para o Proto-Tupí de um processo derivacional que teria formado nomes de objeto a partir de verbos transitivos, por meio de um prefixo **-mi-...