AKTIVITAS ANTIDIARE EKSTRAK ETANOL DAUN NANGKA (Artocarpus heterophyllus Lam.) DAN DAUN ANGSANA (Pterocarpus indicus Wild.) PADA MENCIT JANTAN GALUR BALB/C

ABSTRACT Traditionally, jackfruit leaves (Artocarpus heterophyllus Lam.) and angsana leaves (Pterocarpus indicus Wild.) have been used as an herb for diarrhea treatment. The purpose of this experimental study was to investigate the antidiarrheal effect of jackfruit leaves ethanol extract (JLEE) and angsana leaves ethanol extract (ALEE) on Balb/C male mice with castor oil-induced diarrhea method. The study design is a randomized matched two group post test-only. JLEE and ALEE produced by maceration. An antidiarrheal activity of both of extracts compared with loperamide-HCl 10 mg/Kg BW. JLEE (100, 200 and 400) mg/Kg BW and ALEE (80, 160 and 320) mg/Kg BW significantly (p 0.05). Keywords: Antidiarrheal, castor oil-induced diarrhea,ethanol extract, Artocarpus heterophyllus Lam., Pterocarpus indicus Wild