Zephgrabetaine (1), a new betaine type Amaryllidaceae alkaloid, along with seven known alkaloids, lycorine, galanthine, lycoramine, hamayne, haemanthamine, tortuosine, and ungeremine were isolated from the bulbs of Zephyranthes grandiflora and their structures elucidated by spectroscopic data analysis. The isolated alkaloids were tested for in vitro cytotoxic activities against two cell lines, C-6 (rat glioma cells) and CHO-K1 (Chinese hamster ovary cells). A dose dependent cytotoxic effect was exhibited by all the alkaloids on these two cancer cell lines with prominent activity of lycorine and haemanthamine
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmacognosy and Pharmaceut...
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Bota...
Background and objectives: Many members of the Amaryllidaceae are regarded as toxic. The toxic const...
Amaryllidaceae are known as ornamental plants, furthermore some species of this family contain galan...
Author: Lucie Jánská Název: Alkaloids of family Amaryllidaceae: genus Zephyranthes Diploma thesis Ch...
Summary Natural phytochemicals are currently used in the treatment of many diseases. Cancers are jus...
Twenty-nine Amaryllidaceae alkaloids and their derivatives belonging to the five most common groups,...
The treatment of many diseases is highly dependent on natural products and natural products can also...
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Bot...
The bulbs and aerial parts of Zephyranthes concolor (Lindl.) Benth. & Hook. f. (Amaryllidaceae), an ...
The bulbs and aerial parts of Zephyranthes concolor (Lindl.) Benth. & Hook. f. (Amaryllidaceae), an ...
Fifteen Amaryllidaceae alkaloids (1−15) were evaluated for their antiproliferative activities agains...
Seven new alkaloids, <i>N</i>-methylhemeanthidine chloride (<b>1</b>), <i>N</i>-methyl-5,6-dihydropl...
Hanusová P.: Alkaloids of Amaryllidaceae family: isolation, structural identification, biological ac...
Plants belonging to the Amaryllidaceae family are well known for their ornamental and medicinal use....
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmacognosy and Pharmaceut...
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Bota...
Background and objectives: Many members of the Amaryllidaceae are regarded as toxic. The toxic const...
Amaryllidaceae are known as ornamental plants, furthermore some species of this family contain galan...
Author: Lucie Jánská Název: Alkaloids of family Amaryllidaceae: genus Zephyranthes Diploma thesis Ch...
Summary Natural phytochemicals are currently used in the treatment of many diseases. Cancers are jus...
Twenty-nine Amaryllidaceae alkaloids and their derivatives belonging to the five most common groups,...
The treatment of many diseases is highly dependent on natural products and natural products can also...
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Bot...
The bulbs and aerial parts of Zephyranthes concolor (Lindl.) Benth. & Hook. f. (Amaryllidaceae), an ...
The bulbs and aerial parts of Zephyranthes concolor (Lindl.) Benth. & Hook. f. (Amaryllidaceae), an ...
Fifteen Amaryllidaceae alkaloids (1−15) were evaluated for their antiproliferative activities agains...
Seven new alkaloids, <i>N</i>-methylhemeanthidine chloride (<b>1</b>), <i>N</i>-methyl-5,6-dihydropl...
Hanusová P.: Alkaloids of Amaryllidaceae family: isolation, structural identification, biological ac...
Plants belonging to the Amaryllidaceae family are well known for their ornamental and medicinal use....
Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmacognosy and Pharmaceut...
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Bota...
Background and objectives: Many members of the Amaryllidaceae are regarded as toxic. The toxic const...