MUSCLE PERFORMANCE, SIZE, AND SAFETY RESPONSES AFTER EIGHT WEEKS OF RESISTANCE TRAINING AND PROTEIN SUPPLEMENTATION: A RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED CLINICAL TRIAL

Herda, AA, Herda, TJ, Costa, PB, Ryan, ED, Stout, JR, and Cramer, JT. Muscle performance, size, and safety responses after eight weeks of resistance training and protein supplementation: A randomized, double-blinded, placebo-controlled clinical trial. J Strength Cond Res 27(11): 3091-3100, 2013The purpose of this study was to examine the effects of 2 different types of protein supplementation on thigh muscle cross-sectional area (CSA), blood markers, muscular strength, endurance, and body composition after 8 weeks of low- or moderate-volume resistance training in healthy, recreationally trained, college-aged men. One hundred and six men were randomized into 5 groups: low-volume resistance training with bioenhanced whey protein (BWPLV; n = 22), moderate-volume resistance training with BWP (BWPMV; n = 20), moderate-volume resistance training with standard whey protein (SWPMV; n = 22), moderate-volume resistance training with a placebo (PLA; n = 21), or moderate-volume resistance training with no supplementation (CON; n = 21). Except for CON, all groups consumed 1 shake before and after each exercise session and one each on the nontraining day. The BWPLV, BWPMV, and SWPMV groups received approximately 20 g of whey protein per shake, whereas the BWP groups received 5 g of additional polyethylene glycosylated (PEG) leucine. Resistance training sessions were performed 3 times per week for 8 weeks. There were no interactions (p \u3e 0.05) for muscle strength and endurance variables, body composition, muscle CSA, and safety blood markers, but the main effects for training were observed (p 0.05). However, the Albumin:Globulin ratio for SWPMV was lower (p = 0.037) than BWPLV and BWPMV. Relative protein intake (PROREL) indicated a significant interaction (p \u3c 0.001) with no differences across groups at pre; however, BWPLV, BWPMV, and SWPMV had a greater intake than did PLA or CON at post (p \u3c 0.001). This study indicated that 8 weeks of resistance training improved muscle performance and size similarly among groups regardless of supplementation