Add to ORKGDeoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reported on the design of multi-component deoxyribozyme (MNAzyme) sensors based on 10-23 and 8-17 DNA enzymes. The sensors can detect down to 5 pM of a specific nucleic acid. The versatility of MNAzyme platform allows the design of catalytic cascades for signal amplification. This work is a step forward to PCR-free molecular diagnostics
Molecular beacons represent a new family of fluorescent probes for nucleic acids, and have found bro...
The vast majority of deoxyribozyme-based sensors are designed using modified RNA-cleaving deoxyriboz...
The principal aims of the research in this thesis were to: (i) Create novel molecular switches using...
Deoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reporte...
Deoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reporte...
To increase the versatility and utility of nucleic acid enzymes, we developed multicomponent complex...
The emergence of MNAzymes (Multi-component nucleic acid enzymes) provides a new approach for detecti...
In disease diagnostics, single- and multiplex nucleic acid (NA) detection, with the potential to dis...
Along with biocompatibility, chemical stability, and simplicity of structural prediction and modific...
Deoxyribozymes (Dz), catalytic DNA molecules, are promising tools to design nucleic acid sensors. [....
Along with biocompatibillty, chemical stability, and simplicity of structural prediction and modific...
Biosensors are analytical devices that have found a variety of applications in medical diagnostics, ...
Sensitive DNA assays are of importance in life science and biomedical engineering, but they are heav...
Molecular beacons (MBs) are a novel class of nucleic acid probes that become fluorescent when bound ...
Ribozymes are known to catalyze biochemical reactions and behave like enzymes. They are naturally oc...
Molecular beacons represent a new family of fluorescent probes for nucleic acids, and have found bro...
The vast majority of deoxyribozyme-based sensors are designed using modified RNA-cleaving deoxyriboz...
The principal aims of the research in this thesis were to: (i) Create novel molecular switches using...
Deoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reporte...
Deoxyribozymes are promising biotechnological tools. In a recent JACS article, Mokany et al. reporte...
To increase the versatility and utility of nucleic acid enzymes, we developed multicomponent complex...
The emergence of MNAzymes (Multi-component nucleic acid enzymes) provides a new approach for detecti...
In disease diagnostics, single- and multiplex nucleic acid (NA) detection, with the potential to dis...
Along with biocompatibility, chemical stability, and simplicity of structural prediction and modific...
Deoxyribozymes (Dz), catalytic DNA molecules, are promising tools to design nucleic acid sensors. [....
Along with biocompatibillty, chemical stability, and simplicity of structural prediction and modific...
Biosensors are analytical devices that have found a variety of applications in medical diagnostics, ...
Sensitive DNA assays are of importance in life science and biomedical engineering, but they are heav...
Molecular beacons (MBs) are a novel class of nucleic acid probes that become fluorescent when bound ...
Ribozymes are known to catalyze biochemical reactions and behave like enzymes. They are naturally oc...
Molecular beacons represent a new family of fluorescent probes for nucleic acids, and have found bro...
The vast majority of deoxyribozyme-based sensors are designed using modified RNA-cleaving deoxyriboz...
The principal aims of the research in this thesis were to: (i) Create novel molecular switches using...