COLOROMETRIC DETERMINATION OF RANTIDINE HYDROCHLORIDE

A simple, precise and cost effective colorometric method have been developed for the estimation of Rantidine hydrochloride in its pharmaceutical formulations. RNH shows λmax at 520.0 nm. The drug follows the Beer-Lambert’s law. The method validated by following the analytical performance parameters suggested by the International Conference on Harmonization. All validation parameters were within the acceptable range. The developed methods were successfully applied to estimate the amount of RNH in pharmaceutical dosage form