The effect of vitamin C on ovary of female white rats treated with kmno4. Histological & physiological study

The present study was conducted to verify the oxidative stress status by using different doses of KMno4 (100,200,300) mg /70kg b.w and role of antioxidant agents at different concentrations of Vitamin C (1000, 1500, 2000) mg /70kg b.w on female infertility. To achieve this aim, 72 female rats with ages of 2-3 months, weighing( 180g-250g) Were enrolled .To compare the results, 24 healthy individuals of ages(2-3 months) were also studied which divided to three chief groups: treated with KMno4, Vitamin C and combination of (KMno4+Vitamin C) . Serum Vitamin C and ovaries were dissected for histopathological study. The results indicated a significant decrease (p<0.05) of Vitamin C values in sera of groups that treated with (KMno4) alone, when compared with the control group, while Vitamin C levels showed a significant (p