Standardization and Pharmacological Screening of Naaga Sangu Parpam

The test drug Naaga Sangu Parpam was selected from the Siddha literature Kannusamy paramparai vaithiyam to Standardize and evaluate the Styptic, Anti-inflammatory and Analgesic activities. • The dissertation started with an introduction explaining about the Siddha concept, prevalence of Hemorrhoids and role of the test drug in treating hemorrhoids. • All the ingredients were identified and authenticated by the experts and were purified and the medicine was prepared as mentioned in the Siddha literature. • Review of literature in various categories were carried out. Siddha aspect, botanical aspect, mineralogical aspect and zoological aspect, disclosed about the ingredients of the drug and strongly supported that it possesses Styptic, anti-inflammatory and analgesic activities. • The drug was subjected to qualitative analysis such as physicochemical, phytochemical, chemical analysis. Quantitatively with FTIR, ICP-OES, HR-SEM with EDAX, XRD and TGA analysis which provided the key ingredients present in the drug. Thus it accounts the efficacy of the drug. • Pharmacological studies revealed that the drug Naaga Sangu Parpam exhibited significant styptic, anti-inflammatory and analgesic activities in animal models. • Results and discussion gives the necessary justifications to prove the potency of the drug. • Conclusion gives a compiled form of the study and explains the synergistic effect of all the key ingredients and activities that supports the study. CONCLUSION: From the above analytical studies (i.e. qualitative and quantitative analysis) and pharmacological activities (i.e. Styptic, Anti-inflammatory and Analgesic activities), this study is concluded that the study drug Naaga Sangu Parpam possesses a good Styptic, Anti-inflammatory and Analgesic activities. Finally concluded that the study drug Naaga Sangu Parpam can be used for Moolam (Hemorrhoids), Powthiram (Fistula in ano), Vellai (Leucorrhoea) and Vettai (Venereal disease)