Two component preparation of fibrin glue and its clinical evaluation in split skin grafting: A prospective study

Management of a disrupted tissue is the core of the research in this era and conventional suturing and stapling is painful, time consuming and expensive, tissue adhesives has erupted as a light to this dark. Fibrin glue used in this study is a biological tissue adhesive and is chosen to check for its anchorage, graft uptake, soakage and infection rate. Its two components are fibrinogen and thrombin. Fibrinogen is obtained from cryoprecipitate and thrombin from screened donor’s fresh frozen plasma and the same is applied to 30 patients in the study undergoing split skin grafting. The results were compared to conventional suturing and staples. The fibrin glue tested in the study is a simple, efficacious, cost-effective, less time consuming, better graft uptake, less seroma formation, minimum infection, easy and comfortable intraoperative and post-operative care and patients can be made ambulant early