Typing of hemolytic anemias: Role of basic diagnostic screening panel

In the developing world haemolytic anaemia are becoming a huge disease burden. The diagnostic tests are time consuming and costly as well.in our study we subjected the patients with a clinical suspicion to basic panel of investigations to establish an underlying haemolytic process and tried to categorise haemolytic anemia. Our panel of simple investigations include CBC, peripheral blood smear, reticulocyte count, osmotic fragility test, serum bilurubin, hemoglobinuria and hemosiderinuria. With this panel we were able to diagnose 50% of cases as thalassaemia, 21.42% of caeses as post haemolytic state, 7.145 as haemolytic disease of new born and the remaining as others in which an underlying haemolytic process was established