A Study of Serum Total Calcium and Serum Calcium / Phosphorus Ratio in Essential Hypertension and Its Correlation with Severity of the Disease

INTRODUCTION: Hypertension significantly increases the risk of mortality and morbidity of cerebrovascular accidents (both ischaemic and haemorrhagic), coronary artery disease, congestive heart failure, chronic kidney failure, and peripheral vascular diseases. Hypertension related complications have become one of the most important contributor to preventable deaths and diseases in our country too, with an alarmingly increasing rate in the rural areas. More than 140 million people are said to be suffering from hypertension in India and it has been estimated to overhaul the 214 million mark by 2025. SETTINGS AND DESIGN: A case-control study involving 100 subjects. Subjects were grouped into 50 healthy controls and 50 cases of essential hypertension. Concentrations of serum total calcium and serum calcium phosphorus ratio were measured in the participants and compared in hypertensive patients and normotensive individuals. RESULTS: The study showed that serum total calcium were significantly decreased (p Value <0.001) and serum calcium phosphorus ratio is increased (p Value